Abstract: Objective: To analyze the correlation between anxiety symptoms and Traditional Chinese Medicine(TCM) constitutions of patients at general hospital. Methods:A cross-sectional study was conducted among patients at four general hospitals in Guangzhou. Generalized Anxiety Disorder- 7(GAD- 7) and Patient Health Questionnaire- 9(PHQ- 9) were used to evaluate whether the patients had anxiety and depression symptoms. Classification and Determination of Constitution in TCM was used to identify constitution. Results:Among 1 595 cases of patients,442 patients had anxiety symptoms,accounting for 27.7% . There was no significance in differences being found in the comparison of gender, marital status, nationality, registered residence, present address, occupation, living condition, income, payment method, purposes of medical visit,smoking,and drinking(P>0.05). When compared the constituent ratio of patients with or without family members who had emotional diseases, the difference was significant(P<0.01). According to the analysis and comparison of the medical history data of diabetes,cerebrovascular disease,heart disease and tumor in the two groups,there was no significance in differences(P>0.05);however,there were significant differences being found in the comparison of the medical history date of hypertension and other diseases except the above five diseases(diabetes,cerebrovascular disease,heart disease,and tumor) between the two groups(P<0.01). When compared the age, years of schooling, the scores of nine kinds of TCM constitutions,and the total score of PHQ- 9 between the two groups,there was significance in differences(P<0.01). The score of gentler constitution constitution in the anxiety group was lower than that in the non-anxiety group(P<0.01),and the scores of eight kinds of biased constitution were higher than those in the non- anxiety group(P<0.01). Depression and Qistagnation constitution are the risk factors of anxiety. Anxiety symptoms were negatively correlated with the score of gentler constitution(P<0.01).,and positively correlated with the scores of Qi- deficiency constitution,Qi- stagnation constitution, phlegm- dampness constitution,inherited- special constitution,blood- stasis constitution,Yang- deficiency constitution, Yin-deficiency constitution,and damp-heat constitution(P<0.01). Conclusion:Patients with physical diseases have higher incidence of anxiety symptoms than the general population,suggesting that there is a need to pay attention to the mental health of patients at general hospitals. From the perspective of Chinese medicine constitution,Qi-stagnation constitution is the main risk factor of anxiety symptoms;targeted measures should be taken to improve the constitution of patients as soon as possible,so as to prevent the occurrence of anxiety disorders.