Clinical Study of Suoquan Capsules, Xingpi Yang'er Granules Combined with Moxibustion for Urinary Incontinence with Spleen-Kidney Deficiency Syndrome in Children
Abstract: Objective: To observe the clinical effect of Suoquan capsules, Xingpi Yang'er granules combined with moxibustion for urinary incontinence with spleen- kidney deficiency syndrome in children. Methods:A total of 100 cases of children with urinary incontinence with spleen-kidney deficiency syndrome were selected as the study subjects and divided into the observation group and the control group according to the random number table method,50 cases in each group. The observation group was given the oral administration of Suoquan capsules and Xingpi Yang'er granules,and point moxibustion. The control group was given the oral administration of desmopressin acetate. Both groups were treated for three months. The total clinical efficacy,improvement of Chinese medicine syndrome,bladder volume,residual urine volume,blood arginine vasopressin,urine osmotic pressure,hemoglobin,albumin,adverse reactions and recurrence rate were observed in the two groups. Results: After treatment, scores of spleen- kidney deficiency syndrome in the two groups were decreased when compared with those before treatment,differences being significant(P<0.05);the score in the observation group was lower than that in the control group, the difference being significant(P<0.05). After treatment, bladder volume, blood arginine vasopressin and urine osmotic pressure in the two groups were increased when compared with those before treatment, differences being significant(P<0.05), and residual urine volume was decreased when compared with that before treatment,the difference being significant(P<0.05). After treatment,when compared bladder volume,residual urine volume, urine osmotic pressure, and blood arginine vasopressin between the two groups, there was no significance in differences(P>0.05). After treatment,in the observation group,levels of hemoglobin and albumin were obviously increased when compared with those before treatment,differences being significant(P<0.05). In the observation group,there were no significant differences being found in the comparison of hemoglobin and albumin before treatment and those after treatment(P>0.05). After treatment,hemoglobin and albumin in the observation group were higher than those in the control group,differences being significant(P<0.05). The total effective rate was 84.00% in the observation group,and 80.00% in the control group,no significant difference being found in the comparison between the two groups(P>0.05). During the first three months after treatment,the recurrence rate of children with effective treatment was 7.14% in the observation group, and 25.00% in the control group, the difference being significant(P<0.05). There was one case of mild nausea in the observation group, and the total incidence of adverse reactions was 2.00% ; there were nine cases of mild headache, nausea, and diarrhea in the control group, and such symptoms disappeared after symptomatic treatments, the total incidence of adverse reactions being 18.00%. There was significance being found in the comparison of the total incidence of adverse reactions between the two groups(P<0.05). Conclusion: In the treatment of urinary incontinence in children, the therapy of Suoquan capsules,Xingpi Yang'er granules combined with moxibustion has the advantages of effectiveness,low recurrence rate,and less adverse reactions,and it can help improve physical fitness.