Abstract：Objective：To observe the effect of Tongdu Tiaoshen acupuncture method combined with early rehabilitation training on neurological function，cognitive function，limb motor function，language ability and quality of life of patients with stroke. Methods： A total of 80 cases of patients with stroke were selected and divided into the control group and the observation group according to the random number table method，40 cases in each group. The control group was given early rehabilitation training，and the observation group was additionally treated with Tongdu Tiaoshen acupuncture method based on the treatment of the control group. Both groups were treated for one month. Scores of National Institutes of Health Stroke Scale(NIHSS)，Mini Mental State Examination(MMSE)，simplified Fugl-Meyer Assessment of Motor function，Activities of Daily Living(ADL)， Aphasia Quotient(AQ)，Chinese Functional Communication Profile(CFCP) and Short Form 36 Health Survey Questionnaire(SF- 36) were compared between the two groups before and after treatment. Results： After treatment， scores of NIHSS in the two groups were decreased when compared with those before treatment(P＜0.05)，and scores of MMSE， simplified Fugl- Meyer Assessment of Motor function， ADL， AQ， and CFCP were increased(P＜0.05)； NIHSS score in the observation group was lower than that in the control group(P＜0.05)， and scores of MMSE， simplified Fugl- Meyer Assessment of Motor function，ADL，AQ，and CFCP were higher(P＜0.05). After treatment，scores of physiological function， emotional function and social function in the two groups were increased when compared with those before treatment(P＜0.05)，and the scores of SF-36 in the observation group were higher than those in the control group(P＜0.05). Conclusion： Tongdu Tiaoshen acupuncture method combined with early rehabilitation training can effectively improve neurological function，cognitive function，limb motor function，language ability and quality of life of patients with stroke.