Abstract：General practice is an ideal model of community health service recognized by the world. China has entered the aging society， so it is particularly important to speed up the construction of urban community health service network with community health service center as the main body. Medical colleges and universities should strengthen the education of general medicine for medical students，take the knowledge education and skill training of general medicine as a basic task， and cultivate their ability of community health service. Case discussion is an important way of clinical teaching and graduation practice teaching，whose teaching characteristics can make up for some problems existing in the current graduation practice teaching. Under the background of the community general medicine and the trend of multiple disciplines，case discussion in clinical teaching can integrate cardiovascular，digestive，respiratory，endocrinology and other internal medicine specialties as well as multiple disciplines such as surgery，imaging，endoscopy，rehabilitation，nursing，etc.，to increase undergraduates' perceptual understanding of general practice and meet the needs of community general medicine. Therefore，it can be seen that the multi- disciplinary integration of clinical teaching case discussion mode is in line with the needs of medical clinical， teaching development and the reform of China's medical and health system under the background of community general practice.