补肾活血明目汤对糖尿病视网膜病变患者血糖、视力及炎性因子的影响
DOI:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

R587.2

基金项目:

绍兴市科技计划项目(2017B70044)


Effect of Bushen Huoxue Mingmu Tang on Blood Glucose, Vision and Inflammatory Factors in Patients with Diabetic Retinopathy
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:观察补肾活血明目汤对糖尿病视网膜病变(DR) 患者血糖、视力及炎性因子的影响。方法:按随机数字表法将160 例DR 患者分为治疗组与对照组各80 例。对照组采取羟苯磺酸钙胶囊治疗,治疗组在对照组基础上加用补肾活血明目汤治疗。对比2 组治疗前后空腹血糖(FBG)、餐后2 h 血糖(P2hBG)、糖化血红蛋白(HbA1c)、视力及各炎性因子的变化,比较2 组临床疗效与不良反应发生率。结果:治疗组总有效率为96.25%,高于对照组的86.25% (P<0.05)。与同组治疗前比较,2 组治疗后FBG、P2hBG、HbA1c、肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)、白细胞介素-23(IL-23) 水平及黄斑中心凹厚度均降低(P<0.05),视力升高(P<0.05);与对照组治疗后比较,治疗组治疗后FBG、P2hBG、HbA1c、TNF-α、IL-1β、IL-23 水平及黄斑中心凹厚度均较低(P<0.05),视力较高(P<0.05)。治疗组不良反应发生率为2.50%,低于对照组的11.25%(P<0.05)。结论:补肾活血明目汤治疗DR 患者临床疗效显著,能有效降低患者血糖,提高视力,缓解炎症水平,减少不良反应。

    Abstract:

    Abstract:Objective:To observe the effect of Bushen Huoxue Mingmu tang on blood glucose,vision and inflammatory factors in patients with diabetic retinopathy(DR). Methods:A total of 160 cases of DR patients were divided into the treatment group and the control group according to the random number table method,80 cases in each group. The control group was treated with calcium dobesilate capsules, and the treatment group was additionally treated with Bushen Huoxue Mingmu tang based on the treatment of the control group. The changes of fasting blood glucose(FBG), 2- hour postprandial blood glucose(P2hBG), glycosylated hemoglobin(HbA1c), vision and inflammatory factors before and after treatment in the two groups were compared; the clinical effect and the incidences of adverse reactions in the two groups were compared. Results:The total effective rate was 96.25% in the treatment group,higher than that of 86.25% in the control group(P< 0.05). After treatment, the levels of FBG, P2hBG, HbA1c, tumor necrosis factor- α(TNF- α), interleukin- 1β(IL- 1β), interleukin-23(IL-23) and the central macular thickness in the two groups were decreased when compared with those before treatment(P<0.05),and the vision was increased(P<0.05);the levels of FBG,P2hBG,HbA1c,TNF- α,IL- 1β,IL- 23 and the central macular thickness in the treatment group were lower than those in the control group(P<0.05),and the vision was higher(P<0.05). The incidence of adverse reactions was 2.50% in the treatment group,lower than that of 11.25% in the control group(P<0.05). Conclusion:Bushen Huoxue Mingmu tang has significant clinical effect on DR patients,which can effectively decrease their blood glucose, improve the vision, alleviate the inflammation levels and reduce the adverse reactions.

    参考文献
    相似文献
    引证文献
引用本文

章联欢,官莉莉,孙莉,冯梦雪,王冰清,刘金玲,周健中.补肾活血明目汤对糖尿病视网膜病变患者血糖、视力及炎性因子的影响[J].新中医,2021,53(19):102-105

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2021-10-09
  • 出版日期: