Abstract：Objective：To observe the clinical effect of Yishen Huoxue Jiegu tang assisting reduction and fixation for senile distal radius fracture of kidney deficiency and blood stasis type. Methods： A total of 60 cases of patients with senile distal radial fracture of kidney deficiency and blood stasis type were randomly divided into the treatment group and the control group， 30 cases in each group. The control group was treated with reduction and fixation， and the treatment group was additionally treated with Yishen Huoxue Jiegu tang based on the treatment of the control group. Before and after treatment， Visual Analogue Scale(VAS) scores， swelling degree of the affected side， platelet count(BPC)， thrombin time(TT)， prothrombin time(PT)，and levels of bone mineral density(BMD) and bone metabolism in the two groups were observed，and the clinical effect and incidences of adverse reactions in the two groups were compared. Results：The total effective rate was 96.67% in the treatment group，higher than that of 76.67% in the control group(P＜0.05). After treatment，the VAS scores and swelling degrees in the two groups were decreased when compared with those before treatment(P＜0.05)，and BPC， TT，PT，and levels of BMD，bone alkaline phosphatase(BALP)，carboxyterminal propeptide of type I procollagen(PICP) and bone gla protein(BGP) were increased(P＜0.05). After treatment，the VAS score and swelling degree in the treatment group were lower than those in the control group(P＜0.05)，and BPC，TT，PT and levels of BMD，BALP，PICP and BGP were higher(P＜0.05). There was no significant difference being found in the comparison of adverse reactions between the two groups(P＞0.05). Conclusion： Yishen Huoxue Jiegu tang assisting reduction and fixation for senile distal radial fracture of kidney deficiency and blood stasis type has a good curative effect，which can effectively improve symptoms and coagulation function，reduce pain，and promote bone formation and joint recovery，which is safe and reliable.