Abstract：This paper introduces Prof. ZHAN Qiang's clinical experience in treating shift- work sloth syndrome by using constipation- relieving and zang- fu organs massage. Prof. ZHAN believes that the fundamental reason of sloth syndrome caused by long- term shift work lies in the abnormality of nutrient qi and defensive qi，and disharmony of yin and yang. In terms of syndrome differentiation，the syndromes of it can be divided into heart-spleen deficiency syndrome，phlegm-heat harassing the spirit syndrome， fire- heat liver meridian syndrome and yin deficiency of heart and kidney syndrome. When treating it based on syndrome differentiation，one should keep in mind the following principles：examining their syndromes to know their responses，adjusting the deficiency and excess and normalizing counterflow，and consolidating spleen yang and treating the branches and roots simultaneously. Prof. ZHAN focuses on exquisite manipulation， for example， acupressure and point- pressing method should be applied to the head points and foot points and abdominal eight- trigram method should be applied to the front Mu points. Besides， the manipulation should be changed according to different syndromes： for excessive syndromes， the manipulation should be fast and strong； for deficient syndromes， the manipulation should be slow and soft， and when necessary， massage with ointment can be used to tonify deficiency. Eventually，the goal of activating meridians，self-harmonizing qi and blood，and normalizing yin and yang could be achieved.