针刺头穴联合鼠神经生长因子治疗孤独症谱系障碍患儿临床研究
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R246.6

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Clinical Study on Acupuncture at Scalp Point Combined with Mouse Nerve Growth Factor for Children with Autism Spectrum Disorder
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    摘要:

    目的:观察针刺头穴联合鼠神经生长因子治疗孤独症谱系障碍患儿的疗效及安全性。方法:选取52 例孤独症谱系障碍患儿进行回顾性分析,按患儿不同治疗方案将入选对象分为观察组及对照组。2 组全面测评后行康复训练及注射用鼠神经生长因子治疗,观察组在此基础上加用针刺头穴疗法,2 组均连续治疗3 个月。观察2 组临床疗效,比较2 组治疗前后儿童孤独症评定量表(CARS) 评分及孤独症行为评定量表(ABC) 变化,观察2 组治疗期间不良反应发生情况。结果:治疗后,2 组CARS 评分均较治疗前下降,观察组CARS 评分低于对照组,差异均有统计学意义(P<0.05)。治疗后,2 组感觉、交往、运动、语言、自我照顾能力评分及总分均较治疗前下降,观察组上述6 项评分均低于对照组,差异均有统计学意义(P<0.05)。治疗后,观察组临床疗效总有效率为75.00%,对照组为37.50%,2 组比较,差异有统计学意义(P<0.05)。治疗期间,2 组均未出现明显不良反应。结论:针刺头穴联合鼠神经生长因子对孤独症谱系障碍患儿的临床疗效较好,可改善患儿语言、感觉、交流等能力,且安全性较高。

    Abstract:

    Abstract:Objective:To observe the curative effect and safety of acupuncture at scalp point combined with mouse nerve growth factor for children with autism spectrum disorder. Methods: A total of 52 cases of children with autism spectrum disorder were retrospectively analyzed and divided into the observation group and the control group according to different treatment plans. After comprehensive assessment, both groups were treated with rehabilitation training and mouse nerve growth factor for injection,and the observation group was additionally treated with acupuncture at scalp point. Both groups were treated for three months. The clinical effects in the two groups were observed. Before and after treatment,the changes in the scores of Childhood Autism Rating Scale(CARS) and Autism Behavior Checklist(ABC) in the two groups were compared. During treatment,the incidences of adverse reactions in the two groups were observed. Results:After treatment,CARS scores in the two groups were decreased when compared with those before treatment, and the score in the observation group was lower than that in the control group, differences being significant(P<0.05). After treatment, the scores of sensation,communication,movement,language and self- care ability as well as the total scores in the two groups were decreased when compared with those before treatment,and the above six scores in the observation group were lower than those in the control group,differences being significant(P<0.05). After treatment,the total effective rate of clinical effect was 75.00% in the observation group and 37.50% in the control group, the difference being significant(P<0.05). During treatment,no adverse reaction occurred in the two groups. Conclusion:The therapy of acupuncture at scalp point combined with mouse nerve growth factor for children with autism spectrum disorder has a good clinical effect,and can improve their language,sensation,communication and other abilities with high safety.

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杨美群,李明霞.针刺头穴联合鼠神经生长因子治疗孤独症谱系障碍患儿临床研究[J].新中医,2021,53(21):189-192

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  • 在线发布日期: 2021-11-12
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