Abstract： Objective： To observe the effects of Dachaihu tang combined with electroacupuncture therapy on serum inflammatory factors and gastrointestinal function in patients after laparoscopic cholecystectomy. Methods ： A total of 92 cases of patients undergoing laparoscopic cholecystectomy were divided into the control group and the observation group according to the random number table method， 46 cases in each group. Both groups were given routine anti- infection treatment after operation，the control group was additionally treated with electroacupuncture in four hours after operation， and the observation group was additionally given Dachaihu tang based on the treatment of the control group. The first exhaust time，the first defecation time，the time to get out of bed and the time to return to normal eating after operation，the levels of serum inflammatory factors before operation and in five days after operation as well as postoperative complications and rehabilitation effect of gastrointestinal function in the two groups were observed and compared. Results： After operation， the rehabilitation effect of gastrointestinal function in the observation group was better than that in the control group， the difference being significant(P＜0.05). The first exhaust time， the first defecation time， the time to get out of bed after operation and the time to return to normal eating in the observation group were shorter than those in the control group(P＜ 0.05). Before operation， there was no significant difference being found in the comparison of the levels of tumor necrosis factor-α(TNF-α)，C-reactive protein(CRP） and interleukin-6(IL-6） in serum between the two groups(P＞0.05). In five days after operation，the levels of TNF-α，CRP and IL-6 in serum in the two groups were increased when compared with those before treatment(P＜0.05)，and all the indexes above in the observation group were lower than those in the control group(P＜ 0.05). The incidence of postoperative complications was 4.35% in the observation group and 17.39% in the control group，the difference being significant(P＜0.05). Conclusion： The therapy of Dachaihu tang combined with electroacupuncture for patients after laparoscopic cholecystectomy can promote the recovery of gastrointestinal function，shorten the postoperative rehabilitation time，and reduce the levels of serum inflammatory factors and the incidence of complications.