Abstract： Lymph node metastasis is the most common path of malignant tumors， and the prognosis of malignant tumors is very poor due to metastasis. In Chinese medicine， cancer is considered as the dysfunction of zang- fu organs caused by the internal deficiency of healthy qi， invasion of pathogenic toxin， depressive emotion， diet damage， ongoing diseases and other factors，which causes the abnormal transformation of qi，blood and body fluids. Therefore，it leads to qi stagnation，blood stasis，phlegm coagulation，damp-turbidity and heat toxin，binding into the zang-fu organs and resulting in contention between each other. As time goes by，they accumulate and become into lymph node metastasis. The author believes that the main pathogenesis of lymphatic metastasis of malignant tumors is the binding of phlegm，toxin and blood stasis. In terms of its treatment，the author holds that it is suitable to invigorate blood and dissolve stasis，dissolve phlegm and dissipate masses，and rectify qi and move stagnation if necessary. In terms of clinical prescriptions，the author considers that the modified Huatan Sanjie prescription according to different symptoms(including Spica Prunellae， Radix Ranunculi Ternati，Camptotheca acuminate Decne，Bulbus Fritillariae Thunbergii，Spina Gleditsiae，Sargassum，Thallus Laminariae， Pseudobulbus Cremastrae seu Pleiones， Radix Trichosanthis， Semen Sinapis， Rhizoma Chuanxiong， Rhizoma Pinelliae， Fructus Aurantii，Rhizoma Atractylodis Macrocephalae，Poria，Rhizoma Dioscoreae Bulbiferae and Radix Platycodonis) will lead to a positive therapeutic effect.