Abstract：Objective：To observe the clinical effect of catgut embedment in points on chronic atrophic gastritis(CAG) and its effect on gastrin-17(G-17) and pepsinogen(PG) in serum. Methods：A total of 60 cases of CAG patients were divided into the observation group and the control group according to the random number table method，with 30 cases in each group. The control group was given routine western medicine， and the observation group was additionally treated with catgut embedment in points based on the treatment of the control group. Changes in levels of G- 17， pepsinogen Ⅰ(PG Ⅰ) and pepsinogenⅡ(PGⅡ) in serum as well as Chinese medicine symptom scores before and after treatment were detected in the two groups. Clinical effects and incidence of adverse reactions were observed. Results：The total effective rate was 93.33% in the observation group，significantly higher than that of 73.33% in the control group，the difference being significant(χ 2= 4.320，P=0.038). After treatment，levels of G- 17 and PG I in the two groups were significantly increased when compared with those before treatment， and PG Ⅱ levels were significantly decreased(P＜0.05)； levels of G- 17 and PG Ⅰ in the observation group were higher than those in the control group，and PG II level was lower(P＜0.05). After treatment，scores of stabbing pain of stomach，torpid intake，emaciation，fatigue and lack of strength and epigastric fullness in the two groups were lower than those before treatment，and each score in the observation group was lower than that in the control group(P＜ 0.05). The incidence of adverse reactions was 6.67% in the observation group and 16.67% in the control group，there being no significance in the difference(χ 2=0.228， P=1.456). Conclusion： Catgut embedment combined with routine western medicine has a defined curative effect on CAG，which can significantly improve levels of G-17 and PGⅠin serum and reduce levels of PGⅡ，and improve clinical symptoms with fewer adverse reactions.