穴位埋线治疗慢性萎缩性胃炎临床研究
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R573.3

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丽水市中医院院级杏林科研基金项目(2020XL04)


Clinical Study on Catgut Embedment in Points for Chronic Atrophic GAstritis
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    摘要:

    目的:观察穴位埋线治疗慢性萎缩性胃炎(CAG) 的临床疗效及对血清胃泌素-17(G-17)、胃蛋白酶原(PG) 的影响。方法:将60 例CAG 患者按随机数字表法分为观察组和对照组各30 例。对照组给予常规西药治疗,观察组在对照组基础上联合穴位埋线治疗。检测2 组治疗前后血清G-17、胃蛋白酶原Ⅰ(PGⅠ)、胃蛋白酶原Ⅱ(PGⅡ) 水平、中医症状积分变化,观察2 组临床疗效及不良反应发生情况。结果:观察组总有效率为93.33%,高于对照组73.33%,差异有统计学意义(χ2=4.320,P=0.038)。治疗后,2 组G-17、PGⅠ水平较治疗前显著提高,PGⅡ水平显著降低(P<0.05),且治疗后观察组G-17、PGⅠ水平高于对照组,PGⅡ水平低于对照组(P<0.05)。治疗后,2 组胃刺痛、食少纳呆、消瘦、倦怠乏力、胃脘胀满评分均低于治疗前,且观察组各症状评分低于对照组(P<0.05)。观察组不良反应发生率为6.67%,对照组为16.67%,2 组比较,差异无统计学意义(χ2=0.228,P=1.456)。结论:穴位埋线联合常规西药治疗CAG 临床疗效确切,能显著提高血清G-17、PGⅠ水平,降低PGⅡ水平,改善临床症状,不良反应较少。

    Abstract:

    Abstract:Objective:To observe the clinical effect of catgut embedment in points on chronic atrophic gastritis(CAG) and its effect on gastrin-17(G-17) and pepsinogen(PG) in serum. Methods:A total of 60 cases of CAG patients were divided into the observation group and the control group according to the random number table method,with 30 cases in each group. The control group was given routine western medicine, and the observation group was additionally treated with catgut embedment in points based on the treatment of the control group. Changes in levels of G- 17, pepsinogen Ⅰ(PG Ⅰ) and pepsinogenⅡ(PGⅡ) in serum as well as Chinese medicine symptom scores before and after treatment were detected in the two groups. Clinical effects and incidence of adverse reactions were observed. Results:The total effective rate was 93.33% in the observation group,significantly higher than that of 73.33% in the control group,the difference being significant(χ 2= 4.320,P=0.038). After treatment,levels of G- 17 and PG I in the two groups were significantly increased when compared with those before treatment, and PG Ⅱ levels were significantly decreased(P<0.05); levels of G- 17 and PG Ⅰ in the observation group were higher than those in the control group,and PG II level was lower(P<0.05). After treatment,scores of stabbing pain of stomach,torpid intake,emaciation,fatigue and lack of strength and epigastric fullness in the two groups were lower than those before treatment,and each score in the observation group was lower than that in the control group(P< 0.05). The incidence of adverse reactions was 6.67% in the observation group and 16.67% in the control group,there being no significance in the difference(χ 2=0.228, P=1.456). Conclusion: Catgut embedment combined with routine western medicine has a defined curative effect on CAG,which can significantly improve levels of G-17 and PGⅠin serum and reduce levels of PGⅡ,and improve clinical symptoms with fewer adverse reactions.

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王健,刘兵.穴位埋线治疗慢性萎缩性胃炎临床研究[J].新中医,2021,53(23):201-204

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  • 在线发布日期: 2021-12-10
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