Abstract： This paper introduces the clinical experience of Prof. HONG Minli in treating chronic cough with Guizhi tang. Prof. HONG Minli believes that the main etiology and pathogenesis of chronic cough is the lung qi failing to diffuse because of the deficiency of healthy qi and pathogen lingering and insecurity of exterior qi. In clinical practice，Guizhi tang should be used to treat chronic cough. In the clinical treatment and syndrome differentiation， we should grasp the main syndrome， differentiate the constitution，and modify the prescription according to different syndromes.