Abstract：Objective：To observe the clinical effect of Shexiang Tongxin dropping pills combined with western medicine for stable angina pectoris(SAP). Methods： A total of 98 cases of SAP patients were divided into the control group and the observation group according to different treatment methods，with 49 cases in each group. The control group was treated with western medicine， and the observation group was treated with Shexiang Tongxin dropping pills combined with western medicine. Both groups were treated for four weeks. Chinese medicine syndrome scores， onset frequency and duration of angina pectoris， levels of interleukin- 6(IL- 6)， tumor necrosis factor- α(TNF- α)， high- sensitivity C- reactive protein(hs- CRP) and blood lipid，and distances in Six-Minute Walk Test(6MWT) before and after treatment as well as the clinical effects in the two groups were compared. Results：After treatment，the scores of chest pain，shortness of breath and palpitation in the two groups were decreased when compared with those before treatment(P＜0.05)， and the scores of chest pain， shortness of breath and palpitation in the observation group were lower than those in the control group(P＜0.05). After treatment， the onset frequency of angina pectoris in the two groups was decreased when compared with that before treatment(P＜0.05)，and the duration of angina pectoris was shortened(P＜0.05)；the onset frequency of angina pectoris in the observation group was less than that in the control group(P＜0.05)，and the duration of angina pectoris was shorter(P＜ 0.05). After treatment， the levels of IL- 6， hs- CRP， total cholesterol(TC)， triglyceride(TG) and low- density lipoprotein cholesterol(LDL-C) in the two groups were decreased when compared with those before treatment(P＜0.05)，and the levels of IL-6，hs-CRP，TC，TG and LDL-C in the observation group were lower than those in the control group(P＜0.05)；the levels of high- density lipoprotein cholesterol(HDL- C) in the two groups were increased when compared with those before treatment(P＜0.05)，and the HDL-C level in the observation group was higher than that in the control group(P＜0.05)；the 6 MWT distances in the two groups were increased when compared with those before treatment(P＜0.05)，and the distance in the observation group was larger than that in the control group(P＜0.05). The total effective rate was 93.88% in the observation group， higher than that of 79.59% in the control group(P＜0.05). Conclusion： Shexiang Tongxin dropping pills combined with western medicine for SAP can improve clinical effect，effectively relieve symptom of angina pectoris，reduce levels of inflammatory factors and blood lipid，and increase walking distance.