Abstract: The international development of Chinese medicine industry under the background of One Belt One Road is based on the development of economic globalization. It is an important part of advertising Chinese medicine culture and the soft power of Chinese culture. By analyzing the plight of the internationalization of Chinese medicine industry at present,we need to grasp the development opportunity of One Belt One Road, and enhance investment in research of Chinese medicine,speed up the cultivation of the talents of Chinese medicine,actively use the brand effect of Chinese medicine, strengthen the flow of international trade of Chinese medicine, and to enhance the core competitiveness of Chinese medicine by promoting the development of international standards for Chinese medicine.