平息汤保留灌肠联合益生菌对腺瘤性肠息肉术后的影响
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R735.34

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2018年度金华市公益类科学技术项目(20184180)


Effect of Retention Enema with Pingxi Tang Combined with Probiotics on Patients After Surgery of Intestinal Adenomatous Polyp
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    摘要:

    目的:观察平息汤保留灌肠联合益生菌对腺瘤性肠息肉术后复发率及中医证候的影响。方法:选取80 例腺瘤性肠息肉患者,按随机数字表法将其分为对照组及观察组各40 例。2 组均行内镜下肠息肉切除手术,术后对照组采用益生菌治疗,观察组采用平息汤保留灌肠联合益生菌治疗。比较2 组手术前后中医证候评分变化,比较2 组术后复发率及不良反应发生情况。结果:术后4 周,2 组腹部胀痛、大便稀溏、便血、食欲减退、精神匮乏、畏寒怕冷评分均低于术前,观察组上述6 项评分均低于对照组,差异均有统计学意义(P<0.05)。术后1 年观察组复发率为7.50%,低于对照组25.00%,2 组比较,差异有统计学意义(P<0.05)。术后4 周,观察组不良反应发生率为7.50%,其中腹胀腹痛1 例、便秘1 例、感染1 例;对照组不良反应发生率为27.50%,其中腹胀腹痛5 例、便秘4 例、感染2 例。2 组不良反应发生率比较,差异有统计学意义(P<0.05)。结论:平息汤保留灌肠联合益生菌可缓解腺瘤性肠息肉的临床症状,防止术后肠息肉复发,用药安全性较高。

    Abstract:

    Abstract: Objective: To observe the effect of retention enema with Pingxi tang combined with probiotics on postoperative recurrence rate and Chinese medicine syndrome in patients after surgery of intestinal adenomatous polyp. Methods:A total of 80 cases of patients with intestinal adenomatous polyp were selected and divided into the control group and the observation group according to random number table method,with 40 cases in each group. Both groups were given endoscopic resection of intestinal polyp. After the resection, the control group was treated with probiotics, and the observation group was treated with retention enema with Pingxi tang combined with probiotics. Changes in Chinese medicine syndrome scores before and after surgery,as well as the postoperative recurrence rate and incidence of adverse reactions were compared between the two groups. Results:Four weeks after surgery,scores of abdominal distending pain,sloppy stool, hematochezia, decreased appetite, lassitude of spirit, and fear of cold in the two groups were lower than those before surgery,and the above six scores in the observation group were lower than those in the control group,differences being significant(P<0.05). The postoperative recurrence rate was 7.50% in the observation group,lower than that of 25.00% in the control group,the difference being significant(P<0.05). Four weeks after surgery,the incidence of adverse reactions was 7.5% in the observation group,including one case of abdominal distension and pain,one case of constipation,and one case of infection; the incidence of adverse reactions was 27.5% in the control group, including five cases of abdominal distension and pain, four cases of constipation, and two cases of infection. There was significance being found in the comparison of incidence of adverse reactions between the two groups(P<0.05). Conclusion:The therapy of retention enema with Pingxi tang combined with probiotics can relieve the clinical symptoms of intestinal adenomatous polyp and prevent its postoperative recurrence with high safety.

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徐升,吴敏华,徐芳,祝芳,黄绿澜,陈豪.平息汤保留灌肠联合益生菌对腺瘤性肠息肉术后的影响[J].新中医,2022,54(1):104-107

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  • 在线发布日期: 2022-01-10
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