Abstract：Objective：To observe the curative effect of kidney-tonifying and blood-activating method for thin endometrial infertility and its effect on endometrial thickness，related hormone indexes and endometrial blood flow levels. Methods：A total of 103 cases of patients with thin endometrial infertility were selected as the study subjects，and divided into the control group and the observation group according to the treatment regimens，with 51 and 52 cases respectively. The control group was treated with femoston tablets， and the observation group was additionally treated with kidney- tonifying and bloodactivating prescription based on the treatment of the control group. The clinical effects in the two groups were compared. Before and after treatment， the endometrial thickness， hormones levels and endometrial blood flow parameters were detected，and the ovulation rates and pregnancy rates were counted. Results：The total effective rate was 92.31% in the observation group， higher than that of 74.51% in the control group， the difference being significant(P＜0.05). After treatment， the endometrial thickness in luteal middle phase in the two groups was increased when compared with that before treatment， and the one in the observation group was higher than that in the control group， the difference being significant(P＜0.05). After treatment，the levels of phosphorus(P) and estrogen(E2) in serum in luteal middle phase in the two groups were increased when compared with those before treatment， and the levels in the observation group were higher than those in the control group， the difference being significant(P＜0.05). After treatment， the resistance index(RI)， pulsatility index(PI)， ratio of end- diastolic peak to end- systolic peak(S/D) in luteal middle phase in the two groups were decreased when compared with those before treatment，and the indexes in the observation group were lower than those in the control group， the difference being significant(P＜0.05). There was no significant difference being found in the comparison of ovulation rates and pregnancy rates between the two groups(P＞0.05). Conclusion： Kidney- tonifying and blood- activating method for patients with thin endometrial infertility can promote the growth and development of endometrium， adjust the level of endometrial thickness， improve the clinical symptoms such as sexual indifference and soreness and weakness of waist and knees，regulate relevant hormone indexes and the endometrial blood flow levels，and improve the clinical effect.