Abstract：Objective：To study the administration rules of Prof. GAO Ping in the treatment of immune thrombocytopenia (ITP) based on data mining technology. Methods：A total of 504 prescriptions of 97 patients with ITP treated by Prof. GAO Ping were collected. The relevant data was collated and the frequency， and correlation and clustering of medicine were analyzed by Medcase V3.2 Canggong public medical record data recording and mining system. Results： The core couplet medicinal for syndrome of yin deficiency with effulgent fire consists of Fructus Ligustri Lucidi and Herba Ecliptae， and the core prescription includes Fructus Ligustri Lucidi， Herba Ecliptae， Radix et Rhizoma Rubiae， Radix Scutellariae， Radix Rehmanniae，and Radix et Rhizoma Glycyrrhizae. The core couplet medicinal for syndrome of frenetic movement of blood due to heat consists of Radix Rehmanniae and Radix Scrophulariae， and the core prescription includes Buball Cornu， Radix Rehmanniae， Moutan Cortex， Radix Scrophulariae， Paeoniae Radix Rubra， Spatholobi Caulis and Herba Agrimoniae. The core couplet medicinal for syndrome of spleen deficiency with failure consists of Radix Codonopsis and Rhizoma Atractylodis Macrocephalae， and the core prescription includes Radix Codonopsis， Rhizoma Atractylodis Macrocephalae， Radix Astragali， Radix et Rhizoma Glycyrrhizae， Radix Angelicae Sinensis， Spatholobi Caulis and Herba Agrimoniae. The core couplet medicinal for syndrome of spleen-kidney yang deficiency consists of Semen Cuscutae and Herba Epimedii，and the core prescription includes Herba Epimedii， Fructus Psoraleae， Fructus Ligustri Lucidi， Fructus Schisandrae Chinensis， Radix Rehmanniae Praeparata and Herba Agrimoniae. Conclusion：Treating ITP，Prof. GAO Ping divides the disease into four syndromes which are yin deficiency with effulgent fire，yin deficiency with effulgent fire，frenetic movement of blood due to heat and spleen- kidney yang deficiency， and always pays attention to protecting the spleen and stomach， cooling the blood，hemostasis and resolving stasis，and combines with tonifying the kidney and nourishing the blood.