Abstract： Objective： To observe the clinical effect of Xiaonang Tiaojing tang combined with drospirenone and ethinylestradiol tablets(Ⅱ) for patients with polycystic ovary syndrome(PCOS) and its effect on anti-mullerian hormone(AMH) and endometrial receptivity. Methods：A total of 90 cases of PCOS patients were selected and divided into the control group and the observation group according to the random number table method，with 45 cases in each group. The control group was given drospirenone and ethinylestradiol tablets(II) for routine treatment，and the observation group was additionally given Xiaonang Tiaojing tang based on the treatment of the control group. Before and after treatment， the changes of Chinese medicine syndrome scores，ovarian volumes，numbers of high- quality eggs and antral follicles，hormone levels including luteinizing hormone(LH)，follicle-stimulating hormone(FSH)，estradiol(E2)，testosterone(T)，progesterone(PRG) and prolactin (PRL)，serum AMH and endometrial receptivity in the two groups were compared. Results：After treatment，the scores of primary and secondary symptoms of Chinese medicine syndromes as well as the total scores in the two groups were decreased when compared with those before treatment(P＜0.05)，and the above scores in the observation group were lower than those in the control group， differences being significant(P＜0.05). After treatment， the ovarian volumes and the numbers of antral follicles in the two groups were decreased when compared with those before treatment，and the numbers of high- quality eggs were increased， differences being significant(P＜0.05)； the ovarian volume and the number of antral follicles in the observation group were lower than those in the control group， and the number of high- quality eggs was higher，differences being significant(P＜0.05). After treatment，the levels of LH，T，PRG，PRL and FSH in the two groups were decreased when compared with those before treatment，and E2 levels were increased(P＜0.05)；the levels of LH，T， PRG， PRL and FSH in the observation group were lower than those in the control group， and E2 level was higher， differences being significant(P＜0.05). After treatment，the levels of serum AMH as well as PI and RI in uterine artery in the two groups were decreased when compared with those before treatment(P＜0.05)，and endometrial thickness was increased (P＜0.05)；the level of serum AMH as well as PI and RI in uterine artery in the observation group were lower than those in the control group， and endometrial thickness was higher， differences being significant(P＜0.05). Conclusion： The therapy of Xiaonang Tiaojing tang combined with drospirenone and ethinylestradiol tablets(II) can effectively relieve the clinical symptoms of PCOS，improve ovarian reserve function and endometrial receptivity，and promote follicular development.