Abstract：Through systematically sorting out ZHANG Xichun's understanding of vitality，liver rising and releasing vitality energy，Sanjiao is the channel through which vitality qi runs，and prescriptions to explain ZHANG Xichun's academic thought of the liver governs detoxification. The core of this thought is to converge and consolidate vitality， while treatment emphasizes to condense the liver and invigorate the liver， the medicine selection prefers to use Furctus Corni. The representative prescription is the Laifu Decoction created by ZHANG Xichun，and it is used in the diagnosis and treatment of chronic debilitating diseases represented by chronic heart failure under the guidance of ZHANG Xichun's thought of liver governs detoxification，received better results.