Abstract：Worm medicine can attack and break up the abdominal masses，invigorate blood and dissolve stasis，move qi and harmonize blood，supplement and cultivate healthy qi. Chinese medicine practitioners of all dynasties accumulated rich experience in treating lower abdominal masses with worm medicine. From the theoretical point of Chinese medicine，worm medicine has the functions of searching the masses and unblocking collaterals，combating toxin with toxin and guiding the effects of herbs to specific channels；worm medicine can meticulously go through the whole body and effectively break up the masses， whose therapeutic effect is incomparable to that of vegetation medicine and mineral medicine. Once its mechanism of action is clear， the exact curative effect can be obtained in clinical practice. When combining medicine， attention should be paid to the dosage to prevent allergy，and stop using as soon as the medicine works.