Abstract：Objective：To observe the clinical effect and prognosis of Yiqi yangyin tang combined with routine therapy for chronic heart failure in stable stage. Methods：A total of 82 cases of patients with chronic heart failure in stable stage were selected and divided into the control group and the study group according to the random number table method，with 41 cases in each group. The control group was given symptomatic treatment of routine western medicine，and the study group was additionally treated with Yiqi Yangyin tang based on the treatment of the control group. Both groups were treated for six months. The clinical effects in the two groups were evaluated. Before and after treatment，left ventricular ejection fraction (LVEF)， left ventricular end- systolic dimension(LVESD) and left ventricular end- systolic volume(LVESV) in the two groups were compared. The quality of life was evaluated by Minnesota Living with Heart Failure Questionnaire(MLHFQ). The sixminute walk test(6MWT) distance， readmission rate and mortality in the two groups were counted. Results： The total effective rate was 92.68% in the study group and 80.49% in the control group，and the one in the study group was higher than that in the control group(P＜0.05). After treatment，the LVEF levels in the two groups were increased when compared with those before treatment(P＜0.05)，and the LVEF level in the study group was higher than that in the control group(P＜ 0.05)；the levels of LVESD and LVESV in the two groups were decreased when compared with those before treatment(P＜ 0.05)， and the levels of LVESD and LVESV in the study group were lower than those in the control group(P＜0.05). After treatment，the 6MWT levels in the two groups were increased when compared with those before treatment(P＜0.05)，and the 6MWT level in the study group was higher than that in the control group(P＜0.05)；the MLHFQ levels in the two groups were decreased when compared with those before treatment(P＜0.05)，and the MLHFQ level in the study group was lower than that in the control group(P＜0.05). The readmission rate was 14.63% in the study group，lower than that of 36.59% in the control group，the difference being significant(P＜0.05). Conclusion：Yiqi yangyin tang combined with routine therapy for chronic heart failure in stable stage can improve heart function， walking distance， quality of life， clinical effect and prognosis，and decrease the readmission rate.