Abstract： Objective： To observe the clinical effect of Danxiong Tongluo tang combined with western medicine for hypertensive heart disease. Methods： A total of 100 cases of patients with hypertensive heart disease were selected and divided into the treatment group and the control group according to different treatment methods， with 50 cases in each group. The control group was treated with western medicine，and the treatment group was treated with Danxiong Tongluo tang combined with western medicine. Both groups were treated for four courses， with one week being one course. The changes in the blood pressure including systolic blood pressure(SBP) and diastolic blood pressure(DBP)， the heart function including cardiac index(CI) and cardiac output(CO)， the ventricular morphology including left ventricular left ventricular end diastolic posterior wall thickness(LVPWTD)，left ventricular end diastolic septal thickness(IVSTD)，left ventricular end diastolic diameter(LVEDD) and left ventricular end- systolic dimension(LVESD)， and the ventricular systolic function including mitral valve E point- septal separation(EPSS)， peak E/A wave velocity ratio(E/A)， short axis breaking rate(FS) and left ventricular ejection fraction(LVEF) before and after treatment and the clinical effects in the two groups were compared. Results：After treatment，the values of SBP and DBP in the two groups were decreased when compared with those before treatment，and the values of CI and CO were increased，differences being significant(P＜0.05)；the values of SBP and DBP in the treatment group were lower than those in the control group，and the values of CI and CO were higher，differences being significant(P＜ 0.05). After treatment， the values of LVPWTD， IVSTD， LVEDD and LVESD in the two groups were decreased when compared with those before treatment，and the above four values in the treatment group were lower than those in the control group，differences being significant(P＜0.05). After treatment，the values of EPSS and E/A in the two groups were decreased when compared with those before treatment，and the values of FS and LVEF were increased，differences being significant (P＜0.05)；the values of EPSS and E/A in the treatment group were lower than those in the control group，and the values of FS and LVEF were higher， differences being significant(P＜0.05). After treatment， the total effective rate of clinical effect was 98.0% in the treatment group and 80.0% in the control group，the difference beings significant(P＜0.05). Conclusion： Danxiong Tongluo tang combined with western medicine for hypertensive heart disease has a good clinical effect，and can improve blood pressure and heart function，and promote the decrease of myocardial load.