Abstract：Objective：To observe the effect of ultrasonic fumigation and washing on wound healing and pain after surgery for low perianal abscess. Methods： A total of 60 cases of patients with low perianal abscess were selected and divided into the control group and the study group according to the random number table method，with 30 cases in each group. Both groups were given one-time radical surgery for low perianal abscess，and given routine medicine-changing and anti-infective treatment after surgery. The control group was additionally given sitz bath treatment with fumigation and washing of potassium permanganate solution， and the study group was treated with ultrasonic fumigation and washing. Both groups were treated for 14 days. The clinical effects，wound healing condition，pain degree and incidence of complications in the two groups were compared. Results： The total effective rate was 91.11% in the study group，higher than that of 75.56% in the control group(P＜0.05). The falling time of slough in wound， the drying time of wound， the healing time of wound in the study group were shorter than those in the control group(P＜0.05). One day after surgery， there was no significant difference being found in the comparison of Visual Analogue Scale(VAS) between the two groups(P＞0.05). Three，seven and ten days after surgery，the VAS scores in the study group were lower than those at the same day in the control group (P＜0.05). The incidence of complications was 4.44% in the study group，compared with that of 11.11% in the control group，there was no significant difference being found(P＞0.05). Conclusion：The treatment of ultrasonic fumigation and washing for patients after surgery for low perianal abscess can effectively shorten the healing time of wound，relieve pain and reduce the occurrence of complications after surgery.