Abstract： Objective： To observe the clinical effect of catgut embedment in point combined with amitriptyline for chronic tension headache. Methods：A total of 104 cases of patients with chronic tension headache were selected and divided into the control group and the observation group according to the random number table method， with 52 cases in each group. The control group was treated with amitriptyline，and the observation group was additionally treated with catgut embedment in point based on the treatment of the control group. The clinical effects and the incidences of adverse reactions in the two groups were compared. Before and after treatment，the headache attack frequency，headache duration， pain degree and sleep quality in the two groups were compared. Results： The total effective rate was 94.23% in the observation group， higher than that of 80.77% in the control group(P＜0.05). After treatment， the headache attack frequency and pain degree in the two groups were decreased when compared with those before treatment(P＜0.05)，and the headache duration were shortened(P＜0.05)；the headache attack frequency and pain degree in the observation group were lower than those in the control group(P＜0.05)， and the headache duration was shorter(P＜0.05). After treatment， the scores of insulin sensitivity index(ISI) and Pittsburgh Sleep Quality Index(PSQI) in the two groups were decreased when compared with those before treatment(P＜0.05)，and the scores of ISI and PSQI in the observation group were lower than those in the control group(P＜0.05). The incidence of adverse reactions was 11.54% in the observation group and 7.69% in the control group，there being no significance in the difference(P＞0.05). Conclusion： Catgut embedment in point combined with amitriptyline for chronic tension headache can enhance the curative effect and improve sleep quality with high safety.