益肾排毒汤对慢性肾衰竭患者肾功能和电解质的影响
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R277.5;R692.5

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Effect of Yishen Paidu Tang on Kidney Function and Electrolytes in Patients with Chronic Renal Failure
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    摘要:

    目的:观察益肾排毒汤对慢性肾衰竭(CRF) 患者肾功能和电解质的影响。方法:选取80 例CRF患者按治疗方式不同分为对照组与观察组各40 例。对照组应用西医常规治疗,观察组在对照组基础上加用益肾排毒汤治疗。比较2 组临床疗效及治疗前后肾功能、血脂、炎性因子、电解质水平。结果:观察组总有效率87.50%,高于对照组67.50%(P<0.05)。与同组治疗前比较,治疗后2 组血尿素氮(BUN)、血肌酐(SCr)、24 h 尿蛋白定量、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、白细胞介素-6(IL-6)、白细胞介素-17(IL-17)、C 反应蛋白(CRP)、钾离子(K+)、氯离子(Cl-) 和磷离子(P3-) 水平均降低(P<0.05),钙离子(Ca2+) 水平升高(P<0.05);与对照组治疗后比较,观察组治疗后BUN、SCr、24 h 尿蛋白定量、TC、TG、LDL-C、IL-6、IL-17、CRP、K+、Cl-、P3-水平均较低(P<0.05),Ca2+水平较高(P<0.05)。结论:益肾排毒汤治疗CRF 有较好的疗效,可提高患者肾功能,改善血脂水平,降低炎性因子,恢复电解质水平。

    Abstract:

    Abstract:Objective:To observe the effect of the therapy of Yishen Paidu tang on kidney function and electrolytes in patients with chronic renal failure(CRF). Methods: A total of 80 patients with CRF were selected and divided into the control group and the observation group according to different treatment methods,with 40 cases in each group. The control group was treated with routine treatment of western medicine, and the observation group was additionally treated with Yishen Paidu tang based on the treatment of the control group. The levels of kidney function, blood lipid, inflammatory factors and electrolytes before and after treatment and the clinical effects were compared between the two groups. Results:The total effective rate was 87.50% in the observation group,higher than that of 67.50% in the control group(P<0.05). After treatment, the levels of blood urea nitrogen(BUN), serum creatinine(SCr), 24- hour urine protein, total cholesterol(TC), triglyceride(TG), low- density lipoprotein cholesterol(LDLC), interleukin-6(IL-6),interleukin-17(IL-17),C-reactive protein(CRP),potassium ion(K+ ),chloride ion (Cl- ) and phosphorus ion(P3- ) in the two groups were decreased when compared with those before treatment, and the levels of calcium ion(Ca2 + ) were increased(P<0.05); after treatment, the levels of BUN, SCr, 24- hour urine protein, TC, TG, LDL- C, IL- 6, IL- 17, CRP, K + , Cl- and P3- in the observation group were lower than those in the control group(P<0.05), and the level of Ca2 + in the observation group was higher(P<0.05). Conclusion:The therapy of Yishen Paidu tang has a good curative effect on CRF,which can enhance the kidney function,improve the level of blood lipid,reduce the levels of inflammatory factors,and restore the levels of electrolytes.

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钱莹,李砚民,陈永强.益肾排毒汤对慢性肾衰竭患者肾功能和电解质的影响[J].新中医,2022,54(15):80-83

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  • 在线发布日期: 2022-08-04
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