Abstract：Objective：To observe the preventive effect of the therapy of Shenqi Fuzheng pills combined with point injection on myelosuppression after breast cancer chemotherapy and its effect on cellular immunity. Methods： A total of 98 patients with breast cancer were selected and divided into the control group and the observation group according to the random number table method， with 49 cases in each group. The control group was treated with TC chemotherapy plan， including docetaxel and cyclophosphamide for injection，and was treated for four cycles，21 days being a cycle. The observation group was additionally treated with Shenqi Fuzheng pills combined with point injection based on the treatment of the control group，continuously treated until the end of the chemotherapy. The incidence of myelosuppression after chemotherapy was compared between the two groups. Before and after chemotherapy，the changes of peripheral blood cells，T lymphocyte subsets，states of functional activities and quality of life were observed in the two groups. Results： After chemotherapy， the incidence of myelosuppression was 24.49% in the observation group，lower than that of 46.94% in the control group (P＜0.05). After chemotherapy，the levels of hemoglobin (Hb)，white blood count(WBC) and blood platelet count(BPC) in the two groups were decreased when compared with those before chemotherapy，and the above three levels in the observation group were higher than those in the control group，differences being significant(P＜0.05). After chemotherapy， the levels of CD3 + ， CD4 + and CD8 + in the two groups were decreased when compared with those before chemotherapy，and the above three levels in the observation group were higher than those in the control group， differences being significant(P＜0.05). After chemotherapy， the scores of Karnofsky Performance Scale(KPS) and Short Form- 36(SF- 36) in the two groups were decreased when compared with those before chemotherapy，and the above two scores in the observation group were higher than those in the control group， differences being significant(P＜0.05). Conclusion：The therapy of Shenqi Fuzheng pills combined with point injection can effectively prevent the myelosuppression after breast cancer chemotherapy， enhance the cellular immune function of patients， and improve their functional activities and quality of life.