Abstract： Objective： To observe the clinical effect of the application of Qingchang Xiaoyong tang in assisting laparoscopic appendectomy to treat acute appendicitis. Methods： A total of 110 patients with acute appendicitis were selected and divided into the control group and the observation group according to random number table method，with 55 cases in each group. Both groups were treated with laparoscopic appendectomy under general anesthesia. The control group was treated with routine treatment such as fluid rehydration， anti- infection and maintenance of electrolyte balance， and the observation group was additionally treated with Qingchang Xiaoyong tang based on the treatment of the control group. The recovery of intestinal function and changes of serum inflammatory factors， including hypersensitive Creactive protein(hs- CRP)， tumor necrosis factor- α(TNF- α) and interleukin- 6(IL- 6) were compared between the two groups，and the incidence of complications was analyzed. Results：The recovery time of bowel sounds，anal farting time and defecation time in the observation group were shorter than those in the control group(P＜0.05). Before treatment， there was no significant difference in the levels of serum hs- CRP，TNF-α and IL-6 between the two groups(P＞0.05). After treatment，the levels of serum hs-CRP， TNF- α and IL- 6 in both groups were decreased when compared with those before treatment(P＜0.05)， and the levels of serum hs-CRP，TNF-α and IL-6 in the observation group were lower than those in the control group(P＜0.05). The incidence of complications in the observation group was lower than that in the control group， the difference being significant(P＜0.05). Conclusion： The application of Qingchang Xiaoyong tang in assisting laparoscopic appendectomy to treat acute appendicitis can promote the recovery of intestinal function，reduce the inflammatory responses and reduce the incidence of complications.