Abstract： Objective： To observe the effect of Bushen Liangxue prescription combined with progesterone injection on pregnant hormone levels and pregnancy outcomes of patients with threatened abortion. Methods：A total of 89 cases of patients with threatened abortion were selected and divided into the observation group and the control group according to the random number table method，with 44 cases in each group. The control group was given intramuscular injection with progesterone injection， and the observation group was additionally treated with Bushen Liangxue prescription based on the treatment of the control group. Both groups were treated for two weeks. The clinical effects in the two groups were compared； the changes in the levels of pregnant hormones including estradiol(E2)， human chorionic gonadotropin(β- HCG) and progesterone(P)， uterine artery hemodynamics including resistance index(RI)， end diastolic velocity(EDV) and peak systolic velocity(PSV) in uterine spiral artery as well as pregnancy outcomes before and after treatment in the two groups were compared. Results：The total effective rate was 93.33% in the observation group and 77.27% in the control group，the difference being significant(P＜ 0.05). After treatment，the levels of E2，β-HCG and P in the two groups were increased when compared with those before treatment，and the above three levels in the observation group were higher than those in the control group， differences being significant(P＜0.05). After treatment， the values of RI in the two groups were decreased when compared with those before treatment，and the values of EDV and PSV were increased，differences being significant(P＜0.05). After treatment，RI in the observation group was lower than that in the control group，and the values of EDV and PSV were higher，differences being significant (P＜0.05). The incidence of abortion was 4.44% in the observation group and 20.45% in the control group， the difference being significant(P＜0.05). The incidence of full- term pregnancy was 88.89% in the observation group and 70.45% in the control group，the difference being significant(P＜0.05). Conclusion： The therapy of Bushen Liangxue prescription combined with progesterone injection has a definite clinical effect in the treatment of threatened abortion， which can effectively regulate the levels of pregnant hormones in patients， improve uterine artery hemodynamics， reduce the incidence of abortion and increase the rate of full-term pregnancy.