芪风健中口服液联合耳穴埋针治疗儿童咳嗽变异性哮喘肺脾气虚证临床研究
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R256.12

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上海市宝山区医学特色专科和社区项目(BSZK-2018-A13);上海市宝山区名中医传承工作室建设项目(BSMZYGZS-201906)


Clinical Study on Qifeng Jianzhong Oral Solution Combined with Imbedding Needle at Auricular Points for Children with Cough Variant Asthma with Syndrome of Lung- Spleen Qi Deficiency
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    摘要:

    目的:观察芪风健中口服液联合耳穴埋针治疗儿童咳嗽变异性哮喘肺脾气虚证的临床疗效。方法:选取62 例儿童咳嗽变异性哮喘患儿,按随机数字表法分为中药组及联合组各31 例。2 组均给予中药自制制剂芪风健中口服液治疗,联合组在对照组基础上加用耳穴埋针治疗,2 组疗程均为8 周。比较2 组临床疗效,观察2 组治疗前后咳嗽主症积分、一氧化氮呼出量(FeNO)、免疫指标IgE 的变化。结果:中药组临床疗效总有效率为80.65%,联合组为87.10%,2 组比较,差异无统计学意义(P>0.05)。治疗后,2 组咳嗽主症积分均较治疗前下降,差异均有统计学意义(P<0.05);治疗后,联合组咳嗽主症积分低于中药组,差异有统计学意义(P<0.05)。治疗后,2 组FeNO 指标值均较治疗前下降,联合组治疗前后比较,差异有统计学意义(P<0.05);治疗后,2 组FeNO 指标值比较,差异无统计学意义(P>0.05)。2 组治疗前后IgE 数值比较,差异均无统计学意义(P>0.05)。结论:芪风健中口服液联合耳穴埋针治疗儿童咳嗽变异性哮喘肺脾气虚证的临床疗效较好,可改善患儿咳嗽的症状,能有效遏制患儿气道炎症产物,减少患儿呼吸道急性炎症的发作。

    Abstract:

    Abstract: Objective: To observe the clinical effect of the therapy of Qifeng Jianzhong oral solution combined with imbedding needle at auricular points on children with cough variant asthma with syndrome of lung-spleen qi deficiency. Methods:A total of 62 children with cough variant asthma were selected and divided into the Chinese medicine group and the combination group according to random number table, with 31 cases in each group. The two groups were treated with self-made Qifeng Jianzhong oral solution, and the combination group was additionally treated with imbedding needle at auricular points. The treatment course of both groups was eight weeks. The clinical effects in the two groups were compared, and the changes of the scores of main symptom of cough,fractional exhaled nitric oxide(FeNO) and immune index (IgE) were observed before and after treatment. Results: The total effective rate was 80.65% in the Chinese medicine group and 87.10% in the combination group, there being no significant difference between the two groups(P>0.05). After treatment,the scores of main symptom of cough in both groups were decreased when compared with those before treatment,differences being significant(P<0.05). After treatment, the score of main symptom of cough in the combination group was lower than that in the Chinese medicine group,the difference being significant(P<0.05). After treatment,the levels of FeNO in both groups were decreased when compared with those before treatment, and there was significant difference in the level of FeNO in the combination group before and after treatment(P<0.05). After treatment,the level of FeNO in the two groups,the difference being no significant(P>0.05). There was no significant difference in the level of IgE between the two groups before and after treatment(P>0.05). Conclusion: The therapy of Qifeng Jianzhong oral solution combined with imbedding needle at auricular points has a good clinical effect on the treatment of children with cough variant asthma with syndrome of lung-spleen qi deficiency,which can improve the symptoms of cough in children,effectively curb airway inflammatory products and reduce the onset of acute respiratory tract inflammation.

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姚俊丽,陈黎,黄勋,孔令万.芪风健中口服液联合耳穴埋针治疗儿童咳嗽变异性哮喘肺脾气虚证临床研究[J].新中医,2022,54(17):166-169

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  • 在线发布日期: 2022-09-06
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