Abstract： Objective： To observe the effect of the therapy of thumbtack needle combined with moxibustion and electroacupuncture on bladder function in patients with urinary retention after stroke. Methods：A total of 82 patients with urinary retention after stroke were divided into the control group and the observation group according to the random number table method， with 41 cases in each group. The control group was treated with electroacupuncture combined with moxibustion，and the observation group was additionally treated with thumbtack needle based on the treatment of the control group. The clinical effects were compared between the two groups. Before and after treatment，the related clinical indexes， scores of bladder function，quality of life and incidence of urinary system infection were compared between the two groups. Results：The total effective rate was 95.12% in the observation group and 75.61% in the control group，the difference being significant(P＜0.05). After treatment，the average daily single urination volume in the two groups was increased when compared with those before treatment， and the residual urine volume was decreased， differences being significant(P＜0.05)； after treatment， the average daily single urination volume in the observation group was higher than that in the control group，and the residual urine volume in the observation group was lower，differences being significant(P＜0.05). The hospitalization days and catheter retention time in the observation group were less than those in the control group， differences being significant(P＜0.05). After treatment， the scores of bladder function in the two groups were improved when compared with those before treatment(P＜0.05)，and the improvement in the above score in the observation group was better than that in the control group(P＜0.05). After treatment， the scores of physiological function，mental state，social function and emotional function of quality of life in the two groups were increased when compared with those before treatment， and the above four scores of quality of life in the observation group were higher than those in the control group， differences being significant(P＜0.05). The infection rate was 4.88% in the observation group， with two cases of urinary system infection，and 21.95% in the control group，with nine cases of urinary system infection，and the urinary system infection rate in the observation group was lower than those in the control group， the difference being significant(χ 2=5.145，P=0.023). Conclusion：The therapy of thumbtack needle combined with moxibustion and electroacupuncture for patients with urinary retention after stroke can enhance the clinical effect，improve the bladder function，increase the quality of life，reduce the incidence of urinary system infection，and effectively promote the early recovery of patients.