Abstract： Objective： To observe the clinical effect of Xiao'er Kechuanling oral liquids combined with routine therapy for bronchiolitis in children with phlegm- heat obstructing the lung syndrome. Methods：A total of 82 cases of children with bronchiolitis were selected and divided into the control group and the treatment group according to the random number table method，with 41 cases in each group. The control group was treated with budesonide suspension and salbutamol sulfate solution for inhalation， and the treatment group was additionally treated with Xiao'er Kechuanling oral liquids based on the treatment of the control group. Clinical effects and the disappearance time of clinical symptoms were compared between the two groups. The lung function [tidal volume(TV)，peak time ratio(tPTEF/tE)，peak volume ratio (VPTEF/VE)]， and levels of procalcitonin(PCT) and high- sensitivity C- reactive protein(hs- CRP) before and after treatment in the two groups were compared. Results： The total effective rate was 95.12% in the treatment group， and 75.61% in the control group， the difference being significant(P＜0.05). The disappearance time of cough，panting，moist rale，three-concave sign and other symptoms in the treatment group was obviously shorter than that in the control group，the difference being significant(P＜0.05). Before treatment，there was no significant difference being found in the comparison of the levels of TV，tPTEF/tE and VPTEF/VE between the two groups(P＞0.05). After treatment，TV，tPTEF/tE and VPTEF/VE in the two groups were significantly increased when compared with those before treatment(P＜0.05)，and the above indexes in the treatment group were significantly higher than those in the control group(P＜0.05).Before treatment， there was no significant difference being found in the comparison of the levels of PCT and hs-CRP in serum between the two groups(P＞0.05). After treatment，levels of PCT and hs-CRP in serum in the two groups were significantly decreased when compared with those before treatment(P＜0.05)，and the above two indexes in the treatment group were significantly lower than those in the control group(P＜ 0.05). Conclusion： Based on routine therapy， the additional use of Xiao'er Kechuanling oral liquids for bronchiolitis in children with phlegm- heat obstructing the lung syndrome can improve their symptoms， signs，and the lung function，inhibit inflammatory responses，and enhance clinical effects.