Abstract: This paper introduces the clinical experience of ZHAO Jingwei in the treatment of renal encephalopathy. ZHAO Jingwei holds that renal encephalopathy is located in the kidney and brain,and can affect the heart, the spleen, the liver and other viscera. The four major pathogenesis are deficiency, phlegm, blood stasis and toxin. There are four treatment methods, namely dispelling phlegm and resuscitating, supplementing the kidney and essence, activating the blood to resolve stasis, and unblocking the bowels to purge toxin,which correspond to self- made Xingshen tang,Bushen Shengsui tang,Yiqi Huoxue tang and Tongfu Xingnao Guanchang tang respectively. In clinical practice,the combined application of acupuncture and medication is the key; points with the effect of dispelling phlegm and resuscitating,and tonifying qi and blood are used frequently,and the main points are Baihui point(DU 20), Sishencong point(EX- HN1), Renzhong point(DU 26), Neiguan point(PC 6), Hegu point(LI 4), and Taichong point(LV 3). Based on blood purification, the combined application of various methods can help obtain good curative effects.