Clinical Study on Buyang Huanwu Tang for Ischemic Stroke of Qi Deficiency and Blood Stasis Type
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摘要:
目的:观察补阳还五汤治疗气虚血瘀型缺血性脑中风患者的临床疗效。方法:将80 例缺血性脑中风患者随机分为对照组与治疗组各40 例。对照组采用常规治疗,治疗组在对照组的基础上加用补阳还五汤治疗。比较2 组治疗前后美国国立卫生研究院卒中量表(National Institutes of Health Stroke Scale,NIHSS) 评分、神经功能缺损评分(Neurological Deficit Scale,NDS) 及全血高切黏度、低切黏度、血浆黏度、血小板聚集率、纤维蛋白原。结果:与同组治疗前比较,治疗后2 组NIHSS、NDS 评分均降低(P<0.05);与对照组治疗后比较,治疗组治疗后NIHSS、NDS 评分均较低(P<0.05)。与同组治疗前比较,治疗后2 组全血低切黏度、全血高切黏度、血浆黏度、血小板聚集率及血浆纤维蛋白原均降低(P<0.05);与对照组治疗后比较,治疗组治疗后以上各血液流变学指标均较低(P<0.05)。结论:补阳还五汤联合常规治疗能够显著改善气虚血瘀型缺血性脑中风患者的神经功能缺损,改善脑血流灌注。
Abstract:
Abstract: Objective: To observe the clinical effect of Buyang Huanwu Tang on ischemic stroke patients of qi deficiency and blood stasis type. Methods:A total of 80 patients with ischemic stroke were randomly divided into the control group and the treatment group,with 40 cases in each group. The control group was given conventional treatment, and the treatment group was additionally treated with Buyang Huanwu Tang based on the treatment of the control group. The scores of the National Institutes of Health Stroke Scale(NIHSS) and Neurological Deficit Scale(NDS),and the levels of whole blood high-shear viscosity, low- shear viscosity,plasma viscosity,platelet aggregation rate and fibrinogen were compared between the two groups before and after treatment. Results: When compared with those before treatment, the scores of NIHSS and NDS in the two groups were decreased after treatment(P<0.05); when compared with those in the control group after treatment,the scores of NIHSS and NDS in the treatment group were low after treatment(P<0.05). When compared with those before treatment,the levels of whole blood lowshear viscosity, high-shear viscosity , plasma viscosity, platelet aggregation rate and fibrinogen were decreased in the two groups after treatment(P<0.05); when compared with those in the control group after treatment, the levels of the above hemorheological indexes in the treatment group were low after treatment(P<0.05). Conclusion: The therapy of Buyang Huanwu Tang combined with conventional treatment has significant effect in improving neurological deficits and cerebral blood perfusion in ischemic stroke patients of qi deficiency and blood stasis type.