Abstract: Objective: To observe the clinical effect of blood- letting puncture and heat- sensitive moxibustion combined with modified Chubi Zhuyu Tang for gouty arthritis. Methods:A total of 68 cases of patients with gouty arthritis were selected and divided into the treatment group and the control group according to the random number table method, with 34 cases in each group. Both groups were given routine treatment ; the control group was treated with blood- letting puncture and heat- sensitive moxibustion,and the treatment group was additionally treated with modified Chubi Zhuyu Tang based on the treatment of the control group. Both groups were treated for two weeks continuously. The scores of symptoms including joint pain, joint swelling and activity limitation, the laboratory indexes including erythrocyte sedimentation rate(ESR), blood uric acid(BUA) and C- reactive protein(CRP), as well as the clinical effects in the two groups were compared. Results: The total effective rate was 94.12% in the treatment group and 73.53% in the control group, the difference being significant(P<0.05). Before treatment,there was no significant difference being found in the comparison of the scores of joint pain, joint swelling and activity limitation between the two groups(P>0.05). After treatment,the scores of joint pain,joint swelling and activity limitation in the two groups were significantly decreased when compared with those before treatment(P<0.05),and the improvement of the above indexes in the treatment group was more significant than that in the control group(P<0.05). Before treatment, there was no significant difference being found in the comparison of the levels of ESR,BUA and CRP between the two groups(P> 0.05). After treatment, the levels of ESR, BUA and CRP in the two groups were significantly decreased when compared with those before treatment(P<0.05),and the improvement of the above indexes in the treatment group was more significant than that in the control group(P<0.05). Conclusion:The therapy of blood-letting puncture and heat-sensitive moxibustion combined with modified Chubi Zhuyu Tang for gouty arthritis can significantly improve the clinical symptoms of patients, reduce inflammatory responses and enhance the curative effect.