Abstract：Objective：To observe the clinical effect of acupuncture combined with Runfei Qingzao Tang for chronic bronchitis(CB) in remission stage with lung- kidney yin deficiency syndrome，and its effect on lung ventilation function and immune function of patients. Methods：A total of 138 cases of patients with CB in remission stage with lung- kidney yin deficiency syndrome were selected and divided into the acupuncture group，the decoction group and the combination group according to the random number table method， with 46 cases in each group. All the three groups were given routine western medicine treatment； the acupuncture group was additionally treated with acupuncture； the decoction group was additionally treated with Runfei Qingzao Tang； the combination group was additionally treated with acupuncture combined with Runfei Qingzao Tang. All the three groups were treated for ten days. The clinical effects， traditional Chinese medicine(TCM) syndrome scores， and lung ventilation function， immune function and levels of inflammatory factors in the three groups were compared；the adverse reactions were recorded. Results：The total effective rate was 71.74% in the acupuncture group，76.09% in the decoction group and 91.30% in the combination group；the total effective rate in the combination group was higher than those in the acupuncture group and the decoction group(P＜0.05). After treatment， TCM syndrome scores in the three groups were decreased when compared with those before treatment(P＜0.05)； the TCM syndrome score in the combination group was lower than those in the decoction group and the acupuncture group(P＜0.05)；the TCM syndrome score in the decoction group was lower than that in the acupuncture group(P＜0.05). After treatment，the maximum peak expiratory flow rate(PEF)，vital capacity (VC) and forced expiratory volume in the first second/forced vital capacity(FEV1/FVC) in the three groups were increased when compared with those before treatment(P＜0.05)，and PEF，VC and FEV1/FVC in the combination group were higher than those in the acupuncture group and the decoction group(P＜0.05). After treatment，the levels of CD3+ and CD4+ and the values of CD4+/CD8+ in the three groups were increased when compared with those before treatment(P＜0.05)；the levels of CD3+ and CD4+ and the value of CD4+/ CD8+ in the combination group were higher than those in the acupuncture group and the decoction group(P＜ 0.05)；the levels of CD3 + and CD4 + and the value of CD4 +/CD8 + in the decoction group were higher than those in the acupuncture group(P＜0.05). After treatment， the levels of soluble intercellular adhesion molecule- 1(sICAM- 1) and interleukin- 8(IL- 8) in the three groups were decreased compared with those before treatment(P＜0.05)，and the levels of sICAM-1 and IL-8 in the combination group were lower than those in the acupuncture group and the decoction group(P＜0.05). During treatment，there was no obvious adverse reaction in the three groups. Conclusion： The therapy of acupuncture combined with Runfei Qingzao Tang can effectively inhibit the inflammatory responses of patients with CB in remission stage with lung- kidney yin deficiency syndrome， improve their immune function， promote the recovery of lung ventilation function and relieve clinical symptoms.