Abstract： Objective： To discuss the application effect of Chinese medicine growth paste combined with training exercise for children with idiopathic short stature. Methods：A total of 82 cases of children with idiopathic short stature were selected and given retrospective analysis， and were divided into the observation group and the control group according to their different treatment methods，with 41 cases in each group. The control group was given routine dietary guidance and vitamin D and Licorzine Granules， and the observation group was additionally treated with Chinese medicine growth paste combined with training exercise based on the treatment of the control group. Both groups were treated for two courses， with three months being a course. The clinical effects，the adverse reactions，the increments and growth rates of height in children，and the levels of insulin- like growth factor- 1(IGF- 1) and insulin- like growth factor binding protein-3(IGFBP-3) in the two groups were compared. Results：The total effective rate was 95.12% in the observation group and 78.05% in the control group， the difference being significant(P＜ 0.05). Before treatment，there was no significant difference being found in the comparison of increments and growth rates of height between the two groups(P＞0.05). After three and six months of treatment，the increments and growth rates of height in the two groups were significantly higher than those before treatment(P＜0.05)， and the increments and growth rates of height in the same time point in the observation group were higher than those in the control group(P＜0.05). Before treatment， there was no significant difference being found in the comparison of levels of IGF-1 and IGFBP-3 in serum between the two groups(P＞0.05). After treatment， the levels of IGF- 1 and IGFBP- 3 in the two groups were significantly higher than those in the control group(P＜0.05)，and the levels of IGF- 1 and IGFBP- 3 in the observation group were significantly higher than those in the control group(P＜0.05). During treatment， there was no obvious adverse reactions in the two groups. Conclusion：Based on routine dietary guidance and vitamin D and Licorzine Granules，the intervention of Chinese medicine growth paste combined with training exercise for children with idiopathic short stature can promote the increments and growth rates of height with no obvious adverse reaction.