血府逐瘀汤联合丹参饮加减治疗心血瘀阻型冠心病临床研究
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Clinical Study on Modified Xuefu Zhuyu Tang Combined with Danshen Yin for Coro⁃ nary Heart Disease of Heart Blood Stasis Obstruction Type
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    摘要:

    目的:观察血府逐瘀汤联合丹参饮加减治疗心血瘀阻型冠心病的临床疗效。方法:选取96 例心血 瘀阻型冠心病患者作为研究对象,随机分为对照组和治疗组各48 例。对照组给予常规西药治疗,治疗组在对 照组的基础上给予血府逐瘀汤联合丹参饮加减治疗。比较2 组临床疗效,以及治疗前后中医证候积分、心功能 指标[左室射血分数(LVEF)、左心室舒张末期内径(LVDD)、心率(HR)] 水平变化。结果:治疗组临床 总有效率为95.83%,对照组为83.33%,2 组比较,差异有统计学意义(P<0.05)。治疗前,2 组中医证候积分 比较,差异无统计学意义(P>0.05);治疗后,2 组中医证候积分均较治疗前降低(P<0.05),且治疗组中医 证候积分低于对照组(P<0.05)。治疗前,2 组心功能指标HR、LVDD、LVEF 水平比较,差异无统计学意 义(P>0.05);治疗后,2 组HR、LVDD 均较治疗前降低(P<0.05),LVEF 较治疗前升高(P<0.05),且治 疗组上述指标改善较对照组更显著(P<0.05)。结论:在西医常规治疗的基础上,应用血府逐瘀汤合丹参饮加 减治疗心血瘀阻型冠心病疗效显著,可有效改善患者心功能及中医证候。

    Abstract:

    Abstract: Objective: To observe the clinical effect of modified Xuefu Zhuyu Tang combined with Danshen Yin for coronary heart disease of heart blood stasis obstruction type. Methods:A total of 96 cases of patients with coronary heart disease of heart blood stasis obstruction type were selected as the study subjects, and randomly divided into the control group and the treatment group, with 48 cases in each group. The control group was treated with routine western medicine, and the treatment group was additionally treated with modified Xuefu Zhuyu Tang combined with Danshen Yin based on the treatment of the control group. The changes in traditional Chinese medicine(TCM) syndrome scores and levels of heart function indexes including left ventricular ejection fraction(LVEF), left ventricular end- diastolic diameter (LVDD) and heart rate(HR) before and after treatment and the clinical effects in the two groups were compared. Results:The total effective rate of treatment was 95.83% in the treatment group and 83.33% in the control group, the difference being significant(P<0.05). Before treatment, there was no significant difference being found in the comparison of TCM syndrome scores between the two groups(P>0.05). After treatment, TCM syndrome scores in the two groups were decreased when compared with those before treatment(P<0.05),and the TCM syndrome score in the treatment group was lower than that in the control group(P<0.05). Before treatment,there was no significant difference being found in the comparison of the heart function indexes including HR,LVDD and LVEF between the two groups(P>0.05). After treatment, the levels of HR and LVDD in the two groups were decreased when compared with those before treatment (P<0.05),the LVEF levels were increased,and the improvement of the above indexes in the treatment group was more significant than that in the control group(P<0.05). Conclusion:Based on routine western medicine treatment, the application of modified Xuefu Zhuyu Tang combined with Danshen Yin has a significant curative effect in treating coronary heart disease of heart blood stasis obstruction type and can effectively improve heart function and TCM syndromes.

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张国芳,袁清茹,谢豪杰.血府逐瘀汤联合丹参饮加减治疗心血瘀阻型冠心病临床研究[J].新中医,2022,54(24):42-45

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  • 在线发布日期: 2023-01-01
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