Abstract：Objective：To observe the effect of Guijiao Buxue Syrup in improving anemia after operation for intertrochanteric fracture of deficiency of qi and blood type in senile patients. Methods： A total of 144 cases of patients diagnosed with intertrochanteric fracture and underwent proximal femoral nail antirotation were selected and divided into two groups according to the random number table method， with 72 cases in each group. Both groups were treated with routine treatment， and the treatment group was additionally given the oral administration of Guijiao Buxue Syrup. Both groups were treated for 14 days. The blood loss，and the indexes including hemoglobin(Hb)，hematocrit(Hct) and D-dimer(D-D) before and after operation in the two groups were recorded and compared. The clinical effect in the two groups were compared. Results：After 14 days of treatment，the total effective rate of clinical effect in the treatment group was higher than that in the control group，the difference being significant(P＜0.05). On the first and third days after operation， the Hb levels in the two groups were decreased when compared with those before operation； on the seventh and fourteenth days after operation， the Hb levels in the two groups were increased. On the first，third and seventh days after operation，the Hb levels in the treatment group were lower than those before operation(P＜0.05)， and there was no significance being found in the Hb levels on the fourteenth day after operation and before operation(P＞0.05). On the third， seventh and fourteenth days after operation，the Hb levels in the control group were lower than those before operation (P＜0.05). On the third day after operation，the Hb levels in the two groups were lower than those on the first day after operation(P＜0.05). The Hb level in the treatment group on the seventh day after operation was increased when compared with that on the third day after operation(P＜0.05). The Hb level in the control group on the seventh day after operation was decreased when compared with that on the first day after. On the fourteenth day after operation，the Hb level in the treatment group was higher than that on the first day， third and seventh day after operation(P＜0.05). On the fourteenth day after operation， the Hb level in the control group was lower than that before operation(P＜0.05) and higher than that on the third day after operation(P＜0.05). On the fourteenth day after operation， the Hb level in the treatment group was higher than that in the control group(P＜0.05). On the third day after operation， the total blood loss and hidden blood loss in the treatment group were lower than those in the control group，the difference being significant(P＜0.05)； there was no significant difference being found in the comparison of intraoperative blood loss between the two groups(P＞0.05). On the first and third days after operation，the Hct levels in the two groups were decreased when compared with those before operation， and on the seventh and fourteenth days after operation，the Hct levels in the two groups were increased. On the third and seventh days after operation， the Hct levels in the treatment group were lower than those before operation(P＜ 0.05)， and there being no significant difference being found in the comparison of the Hct level on the fourteenth day after operation and before operation(P＞0.05). On the third， seventh and fourteenth days after operation，the Hct levels in the control group were lower than those before operation(P＜0.05). On the third day after operation， the Hct levels in the two groups were lower than those on the first day after operation(P＜0.05)，and the Hct levels on the seventh day after operation were increased when compared with that on the third day after operation(P＜0.05). the Hct level on the fourteenth day after operation in the treatment group was increased when compared with that on the first，third and seventh day after operation (P＜0.05). The Hct level on the fourteenth day after operation in the control group was lower than that before operation(P＜0.05) and higher than that on the third day after operation(P＜0.05). On the fourteenth day after operation， the Hct level in the treatment group was higher than that in the control group(P＜0.05). Conclusion： After operation， the senile patients with intertrochanteric fracture who take Guijiao Buxue Syrup can reduce the hidden blood loss，improve the symptoms of anemia and deficiency of qi and blood and promote rehabilitation，without increasing the risk of thrombosis.