Abstract：Objective：To observe the curative effect of Xiao'er Feire Kechuan Granules combined with Budesonide Suspension for Inhalation and Ipratropium Bromide Solution for Inhalation for children with asthmatic bronchitis of phlegm- heat obstructing the lung type. Methods：A total of 110 cases of children with asthmatic bronchitis of phlegm- heat obstructing the lung type were enrolled and divided into the intervention group and the control group according to the random number table method，with 55 cases in each group. Based on measures for relieving cough， anti- infection and oxygen inhalation， both groups were treated with Budesonide Suspension for Inhalation and Ipratropium Bromide Solution for Inhalation； the intervention group was additionally treated with Xiao'er Feire Kechuan Granules. Both groups were treated for seven days. Before and after treatment， lung function indexes including forced expiratory volume in the first second(FEV1)，forced vital capacity(FVC)，FEV1/FVC and peak expiratory flow(PEF)，and inflammatory indexes including interleukin(IL) -4，IL-6，IL-10 and interferon-γ(IFN-γ) in the two groups were evaluated. The clinical effects in the two groups were evaluated. Results： After seven- day treatment，the total effective rate was 96.36% in the intervention group and 81.82% in the control group， the difference being significant(P＜0.05). After treatment，the levels of FEV1，FVC，FEV1/FVC and PEF in the two groups were increased when compared with those before treatment， the difference being significant(P＜0.01)；the indexes in the intervention group were higher than those in the control group，the difference being significant(P＜0.01). The levels of IL-4，IL-6 and IL-10 in the two groups were decreased when compared with those before treatment，and the levels of IFN-γ were increased，differences being significant(P＜0.01). The levels of IL-4，IL-6 and IL-10 in the intervention group were lower than those in the control group，and the level of IFN-γ was higher，differences being significant(P＜0.01). Conclusion： Bases on aerosol inhalation with Budesonide Suspension for Inhalation and Ipratropium Bromide Solution for Inhalation，the additional application of Xiao'er Feire Kechuan Granules for asthmatic bronchitis of phlegmheat obstructing the lung type can improve the clinical effect， reduce the inflammation of children， enhance the immune function of body，and promote the recovery of lung function.