Abstract：Objective：To observe the clinical effect of the therapy of Xingqi Huoxue Huayu Decoction combined with rehabilitation exercise for lumbar disc herniation(LDH). Methods：A total of 70 patients with LDH were selected and divided into the control group and the observation group according to the random number table method， with 35 cases in each group. The control group was treated with routine western medicine， and the observation group was additionally treated with Xingqi Huoxue Huayu Decoction combined with rehabilitation exercise based on the treatment of the control group. The clinical effects， traditional Chinese medicine(TCM) syndrome scores， lumbar function， degree of pain and inflammatory responses in the two groups were compared. Results： The total effective rate was 91.43% in the observation group，higher than that of 68.57% in the control group(P＜0.05). After treatment，each TCM syndrome score in the two groups was decreased when compared with that before treatment(P＜0.05)， and each TCM syndrome score in the observation group was lower than that in the control group(P＜0.05). After treatment，the scores of Japanese Orthopaedic Association(JOA) in the two groups were increased when compared with those before treatment，and the scores of Oswestry Disability Index(ODI) and Visual Analogue Scale(VAS) were decreased(P＜0.05)； the score of JOA in the observation group was higher， and the scores of ODI and VAS in the observation group were lower than those in the control group(P＜ 0.05). After treatment，the levels of TNF-α and IL-1β in the two groups were decreased when compared with those before treatment(P＜0.05)；the above levels in the observation group were lower than those in the control group(P＜0.05). Conclusion： The therapy of Xingqi Huoxue Huayu Decoction combined with rehabilitation exercise has a significant rehabilitation effect on LDH， which can alleviate the clinical symptoms of patients， improve lumbar function， relieve pain， reduce inflammatory responses， and is good for promoting recovery.