follow up for 2 weeks. The clinical effects，the first defecation time，the frequency of defecation and the recurrence rate in the two groups were compared； the levels of fasting blood glucose(FBG)， 2- hour postprandial blood glucose(P2hBG) and fructosamine as well as the scores of constipation symptoms， Patient Assessment of Constipation Quality of Life(PAC- QOL)，Kolcaba's General Comfort Questionnaire (GCQ) and WHO- 5 Well- Being Index(WHO- 5) before and after treatment in the two groups were compared；the adverse reactions in the two groups were recorded. Results：The total effective rate was 93.33% in the observation group， higher than that of 73.33% in the control group(P＜0.05). The first defecation time in the observation group was shorter than that in the control group(P＜0.05). During the treatment，the frequency of defecation in the observation group was higher than that in the control group (P＜0.05). After treatment，there was no significant difference being found in the comparison of the levels of fructosamine and FBG between the two groups；before and after treatment，there was no significant difference being found in the comparison of the levels of P2hBG in the control group(P＞0.05)；the level of P2hBG in the observation group was decreased when compared with that before treatment，and was lower than that in the control group(P＜0.05). After treatment， the scores of constipation symptoms and PACQOL in the two groups were decreased when compared with those before treatment(P＜0.05)， and the scores of GCQ and WHO-5 were increased(P＜0.05). The scores of constipation symptoms and PAC-QOL in the observation group were lower than those in the control group(P＜0.05)，and the scores of GCQ and WHO-5 were higher(P＜0.05). After 2-week follow-up，the recurrence rate was 10.71% in the observation group， lower than that of 36.36% in the control group(P＜0.05). During the treatment， there was no obvious adverse reaction in the two groups. Conclusion：When compared with simple treatment of Maren Pills， the therapy of thumbtack needle combined with Maren Pills for diabetes mellitus complicated with constipation can better improve the constipation symptoms of patients，and enhance their quality of life and indexes of well-being，with a low recurrence rate.