Abstract： This paper introduces the clinical experience of Professor HE Shidong in treating severe pneumonia with the method of reinforcing healthy qi and resolving phlegm combined with medication method based on the theory of midnight-midday ebb flow and the zang-fu organs. Prof. HE believes that severe pneumonia is manifested in the lung， the root of the disease lies in the spleen， and its core mechanisms are qi deficiency， blood stasis， and phlegm obstruction. When it is complicated with pulmonary encephalopathy， the upper body is harassed by phlegm turbidity， the heart and mind are clouded，and yang qi is depressed. In clinical practice，he holds an opinion that the method of reinforcing healthy qi and resolving phlegm should be adopted with the focus of invigorating the spleen to tonify qi and resolve phlegm and directing qi downward to relieve cough and asthma，which should be regarded as the main treating principle and method during the treatment of severe pneumonia. When it is complicated with pulmonary encephalopathy，the treatment should be mainly focus on resolving phlegm and eliminating the pathogenic factors， so as to awaken the brain and open the orifices. Meanwhile， with the basis of inheriting the academic thought of Prof. YANG，the medication method based on the theory of midnightmidday ebb flow and the zang-fu organs is summarized，and the best medication time can be selected to improve the clinical effect. In conclusion， good results can be achieved when the method of reinforcing healthy qi and resolving phlegm combined with medication method based on the theory of midnight-midday ebb flow and the zang-fu organs is applied in treating severe pneumonia.