Abstract： Objective： To observe the curative effect of Qiju Dihuang Pills combined with herbal fumigation for dry eye after cataract surgery and its effects on levels of tear inflammatory factors and lysozyme. Methods：A total of 102 cases of patients with dry eye after cataract surgery were selected and divided into the control group and the study group according to the random number table method， with 51 cases in each group. The control group was treated with sodium hyaluronate eye drops ， and the study group was additionally treated with Qiju Dihuang Pills combined with herbal fumigation based on the treatment of the control group. Levels of interleukin- 1 (IL- 1)， interleukin- 1β (IL- 1β)， tumor necrosis factor (TNF- α)， lysozyme， lipid peroxide (LPO)， malondialdehyde (MDA)， and superoxide dismutase (SOD) in the two groups before and after treatment were compared. The wetting value of tears was measured by Schirmer's test (SIt)； corneal injury of patients was evaluated by fluorescent staining (FL)；tear break-up time (BUT) was recorded；clinical effects in the two groups were evaluated. Results： The total effective rate was 94.12% in the study group，higher than that of 80.39% in the control group (P＜ 0.05). After treatment， the levels of IL- 1， IL- 1β and TNF- α in the two groups were decreased when compared with those before treatment， and levels of lysozyme were increased (P＜0.05)； the levels of IL-1，TNF-α，and IL-1 β in the study group were lower，and the level of lysozyme was higher than those in the control group (P＜0.05). After treatment，the levels of SOD in the two groups were increased when compared with those before treatment，and the levels of MDA and LPO were decreased (P＜0.05)；SOD level in the study group was higher，and levels of MDA and LPO were lower than that in the control group (P＜0.05). After treatment， the wetting value of tears and BUT levels in the two groups were increased when compared with those before treatment，and FL scores were decreased (P＜0.05)；the wetting value of tears and BUT levels in the study group were higher，and FL score was lower than those in the control group (P＜0.05). Conclusion：The therapy of Qiju Dihuang Pills combined with herbal fumigation for patients with dry eye after cataract surgery can reduce oxidative stress injury， the levels of tear inflammatory factors，and corneal injury，enhance the levels of lysozyme，promote tear secretion，and improve clinical effects.