Abstract： Objective： To observe the clinical effect of Bushen Quyu Formula assisting treatment for patients after photoselective vaporization of the prostate (PVP) for benign prostatic hyperplasia (BPH) and its effect on urination function and levels of sex hormones. Methods：A total of 120 cases of patients with BPH after PVP were divided into the western medicine group and the comprehensive group according to the method of random sampling，with 60 cases in each group. After operation，the western medicine group was given routine intervention and Tamsulosin Hydrochloride Sustained- Release Tablets ， and the comprehensive group was additionally treated with Bushen Quyu Formula based on the treatment of the western medicine group. The clinical effects，improvement of symptoms，urination function，levels of sex hormones and adverse reactions were compared between the two groups. Results： Before treatment， there was no significant difference being found in the comparison of scores of International Prostate Symptom Score (IPSS) and Overactive Bladder Symptom Score (OABSS) between the two groups (P＞ 0.05). After treatment，the scores of IPSS and OABSS in the two groups were decreased when compared with those before treatment (P＜0.05)，and the scores in the comprehensive group were lower than those in the western medicine group (P＜0.05). The total clinical effective rate was 95.00% in the comprehensive group，higher than that of 81.67% in the western medicine group (P＜0.05). Before treatment，there was no significant difference being found in the comparison of maximal urinary flow rate (Qmax)， post- void residual (PVR)， frequency of urination during daytime and at night， and number of urgent urination between the two groups (P＞0.05). After treatment，the PVR，frequency of urination during daytime and at night， and number of urgent urination were decreased in the two groups (P＜0.05)， and the Qmax was increased (P＜0.05)；the PVR，frequency of urination during daytime and at night，and number of urgent urination in the comprehensive group were less than those in the western medicine group (P＜0.05)，and Qmax was larger than that in the western medicine group (P＜0.05). Before treatment， there was no significant difference being found in the comparison of the levels of testosterone (T)， prolactin (PRL)， estradiol (E2) and luteinizing hormone (LH) in serum between the two groups (P＞0.05). After treatment，the levels of T and PRL in serum were increased (P＜0.05)，and levels of E2 and LH were decreased (P＜0.05)； the levels of T and PRL in serum in the comprehensive group were higher than those in the western medicine group (P＜0.05)，and levels of E2 and LH were lower than those in the western medicine group (P＜0.05). There was no significant difference being found in the comparison of the incidence of adverse reactions between the two groups (P＞0.05). Conclusion： Bushen Quyu Formula assisting treatment for patients after PVP for BPH can improve the clinical effect by reducing urethral pressure，improving urination function， regulating improvement of symptoms and levels of sex hormones， and decreasing the occurrence of urethral stimulation，gastrointestinal reactions and other adverse reactions.