Abstract： Objective： To observe the clinical effect of Xiaogan Jianpi Soft Extract for infantile malnutrition syndrome of mild malnutrition type and its effect on traditional Chinese medicine (TCM) syndrome scores and nutritional status. Methods：A total of 60 cases of infantile malnutrition syndrome of mild malnutrition type were randomly divided into the observation group and the control group ， with 30 cases in each group. The observation group was given the oral administration with Xiaogan Jianpi Soft Extract，and the control group was treated with conventional Chinese medicine formula granules. Clinical effects，the improvement time of clinical symptoms，TCM syndrome scores，and nutritional status were compared between the two groups. Results： The total effective rate was 90.00% in the observation group，higher than that of 66.67% in the control group (P＜0.05). After treatment，the improvement time of remission of abdominal distention，increased body mass，appetite，and complexion in the observation group was shorter than that in the control group (P＜0.05). Before treatment， there was no significant difference being found in the comparison of TCM syndrome scores between the two groups (P＞0.05)； after treatment，TCM syndrome scores in the two groups were decreased (P＜0.05)，and the scores in the observation group were lower than those in the control group (P＜0.05). Before treatment，there was no significant difference being found in the comparison of the contents of hemoglobin (Hb)， iron and zinc between the two groups (P＞0.05)；after treatment，the contents of Hb，iron and zinc in the two groups were increased when compared with those before treatment (P＜0.05)， and the contents in the observation group were higher than those in the control group (P＜0.05). Conclusion：Xiaogan Jianpi Soft Extract has a significant curative effect in the treatment of infantile malnutrition syndrome of mild malnutrition type， and is helpful for the early recovery of the disease and the improvement of clinical symptoms and nutritional status.