Abstract：Drug eruption is a common adverse reaction caused by targeted drugs for liver cancer and it imposes great effects on the treatment and quality of life of patients with liver cancer. The therapy of warming-needle moxibustion combines acupuncture with moxibustion，which thus gives a full play to the effects of venting heat to the outside and warm- reinforcing healthy qi of moxibustion as well as dredging and unlocking the channels and collaterals of acupuncture. It is found that warming- needle moxibustion has a good clinical effect on drug eruption caused by targeted drugs for liver cancer in actual practices. This therapy can well mitigate the symptoms of drug eruption of patients with no effects on their treatment and is highly acceptable in clinical. In addition to their own clinical experience， the authors combed and summarized the experience of treating drug eruption caused by targeted drugs for liver cancer by warming- needle moxibustion after deeply studying the introductions to the drug eruption caused by targeted drugs for liver cancer in traditional Chinese medicine，the effect of moxibustion on drug eruption， the smearing effects of old ginger oil and Blumea oil and the point locating and manipulations of warmingneedle moxibustion，so that they can provide some guidelines for other phycicans.