Abstract： Objective： To observe the clinical effect of Jintiange Capsules in adjuvant therapy of percutaneous vertebroplasty (PVP) for osteoporotic thoracolumbar vertebral fractures. Methods：A total of 116 cases of patients with osteoporotic thoracolumbar vertebral fractures were divided into the control group and the observation group according to the random number table method， with 58 cases in each group. Both groups were treated with PVP. On postoperative day 2， the control group could take appropriate out- of- bed activities and started to take western medicine for anti- osteoporosis treatment； the rehabilitation training was started 1 week after the PVP. The observation group was additionally treated with Jintiange Capsules based on the treatment of the control group from postoperative day 2. Both groups were given 3- month treatment and 1- year follow- up. Traditional Chinese medicine (TCM) syndrome scores and the bone mineral density of the thoracic and lumbar spine 3 months before and after operation， the occurrence rates of complications and fracture recurrence rates within the first year after surgery，and clinical effects were compared between the two groups. Results： 3 months after operation， the total effective rate of clinical effects was 98.28% in the observation group， higher than that of 87.93% in the control group， the difference being significant (P＜0.05). The scores of local swelling pain in the chest， stabbing pain in the lumbar spine， soreness and weakness of the low back and knee， wilting and weakness of lower extremities， difficulty walking， and tinnitus in the two groups were decreased when compared with those before operation (P＜0.05)，and the above 6 TCM syndrome scores in the observation group were lower than those in the control group (P＜0.05). The bone mineral density of the thoracic and lumbar spine in the observation group were enlarged before operation and were larger than those in the control group (P＜0.05). A year after surgery， the occurrence rate of complications was 6.90% in the observation group， lower than that of 20.69% in the control group， the difference being significant (P＜ 0.05). The fracture recurrence rate was 8.62% in the observation group，lower than that of 22.41% in the control group， the difference being significant (P＜0.05). Conclusion： Jintiange Capsules in adjuvant therapy of PVP for osteoporotic thoracolumbar vertebral fractures can enhance clinical effects， relieve clinical symptoms， reduce complications， increase the bone mineral density of the thoracic and lumbar spine，and avoid the recurrence of fractures.