Abstract：Objective：To observe the effect of Wangbi Capsules combined with distraction therapy on lumbar disc herniation complicated with sciatica. Methods：A total of 60 cases with lumbar disc herniation complicated with sciatica of the type of liver-kidney insufficiency and wind-damp obstructing the collaterals were randomly divided into the trial group and the control group， with 30 cases in each group. The two groups were treated with distraction therapy and the trial group was additionally treated with Wangbi Capsules. Both groups were treated for 28 days. The scores of Visual Analogue Scale (VAS) and Japanese Orthopaedic Association (JOA) of low back pain were evaluated before and after treatment in the two groups. The clinical effects and the occurrence of adverse reactions in the two groups were analyzed，and their safety was evaluated. Results：After treatment，the total effective rate of clinical effect was 93.33% in the trial group and 66.67% in the control group，the difference being significant between the two groups (P＜0.05). The scores of JOA low back pain in both groups were increased when compared with those before treatment (P＜0.05)；the score of JOA low back pain in the trial group was higher than that in the control group (P＜0.05). The VAS scores of pain in sciatic nerve distribution in both groups were decreased when compared with those before treatment (P＜0.05)；the VAS score of pain in the trial group was lower than that in the control group (P＜0.05). In the trial group，one patient had liver function impairment，which was improved after taking hepatoprotective medicine， and no other treatment- related adverse reactions were observed. Conclusion： The application of Wangbi Capsules combined with distraction therapy can effectively relieve the low back pain， sciatica and other related symptoms in patients with lumbar disc herniation complicated with sciatica， which is safe and can promote the restoration of lumbar interstitial space and speed up recovery.