Clinical Study on Erchen Decoction and Sanzi Yangqin Decoction Combined with Western Medicine for Chronic Obstructive Pulmonary Disease of Phlegm Turbidity Obstructing the Lung Type
Abstract:Objective:To observe the clinical effect of Erchen Decoction and Sanzi Yangqin Decoction combined with western medicine on chronic obstructive pulmonary disease (COPD) of phlegm turbidity obstructing the lung type. Methods:A total of 98 patients with COPD of phlegm turbidity obstructing the lung type were divided into the control group and the treatment group according to the random number table method, with 49 cases in each group. The control group was given routine western medicine, and the treatment group was additionally treated with Erchen Decoction and Sanzi Yangqin Decoction based on the treatment of the control group. Before and after treatment, the traditional Chinese medicine (TCM) syndrome scores,forced expiratory volume in one second (FEV1),forced vital capacity (FVC) of expected value, percentage of FEV1 and FVC (FEV1/FVC) and scores of World Health Organization Quality of Life- Brief Version (QOL- BREF) in the two groups were compared, and the clinical effects and incidence of adverse reactions were also evaluated. Results:After treatment,the total effective rate in the treatment group was higher than that in the control group (P<0.05). After treatment,the TCM syndrome scores of sputum quality, sputum volume, wheezing and cough in both groups were decreased when compared with those before treatment (P<0.05),and the above scores in the treatment group were lower than those in the control group (P<0.05). After treatment,the FEV1,FVC,FEV1/FVC and QOL- BREF scores in the two groups were significantly higher than those before treatment (P<0.05), and the indexes of lung function and QOL- BREF scores in the treatment group were higher than those in the control group (P< 0.05). No serious adverse reactions occurred in both groups. Conclusion: Erchen Decoction and Sanzi Yangqin Decoction combined with western medicine has a definite curative effect on COPD of phlegm turbidity obstructing the lung type,which can effectively improve the lung function of patients and enhance the quality of life,with good safety.