Abstract：Objective：To observe the clinical effect of Yiqi Huoxue Tongluo Decoction combined with Xingnaojing Injection on patients with cerebral hemorrhage based on routine therapies. Methods：A total of 70 patients with cerebral hemorrhage with qi deficiency and blood stasis syndrome were included and divided into the control group and the observation group according to the random number table method， with 35 cases in each group. The two groups were given routine therapies， including dehydration for lowering intracranial pressure，oxygen inhalation and maintaining water and electrolyte balance，as well as Xingnaojing Injection， and the observation group was additionally treated with Yiqi Huoxue Tongluo Decoction. The two groups were treated for 14 days. Before treatment and after fourteen days of treatment，the traditional Chinese medicine (TCM) syndrome scores in both groups were determined，the neurological function of patients were evaluated by Chinese Stroke Scale (CSS)， the mean blood velocity and peripheral resistance of cerebral vessel were detected by cerebral vessel hemodynamic analysis，the peak systolic velocity (Vs)，mean blood velocity (Vm) were detected by hemodynamic monitor and levels of tumor necrosis factor-α (TNF-α)，interleukin-10 (IL-10)，retinol binding protein 4 (RBP4) and chemokine receptor-4 (CXCR-4) were detected. The clinical effects in the two groups were compared. Results：After fourteen days of treatment，the total clinical effective rate in the observation group was higher than that in the control group (P＜0.05). The CSS scores and TCM syndrome scores of shortness of breath and lack of strength， hemianesthesia， dysphasia and hypoesthesia in both groups were decreased when compared with those before treatment，differences being significant (P＜0.05)；the above 5 scores in the observation group were lower than those in the control group (P＜0.05). The mean blood velocity of cerebral vessel，Vs and Vm in both groups were increased when compared with those before treatment， and the peripheral resistance of cerebral vessel was reduced，differences being significant (P＜0.05)；the mean blood velocity of cerebral vessel，Vs and Vm in the observation group were faster than those in the control group，and the peripheral resistance of cerebral vessel was less， differences being significant (P＜0.05). Compared with those before treatment，the levels of TNF-α and RBP4 in the two groups were decreased，and the levels of IL- 10 and CXCR- 4 were increased，differences being significant (P＜0.05)；the levels of TNF- α and RBP4 in the observation group were lower than those in the control group， and the levels of IL- 10 and CXCR- 4 were higher， differences being significant (P＜0.05). Conclusion： Based on routine therapies， Yiqi Huoxue Tongluo Decoction combined with Xingnaojing Injection for patients with cerebral hemorrhage with qi deficiency and blood stasis syndrome can well enhance the function of cerebral vessel，recover the neurological function， mitigate the inflammatory responses， improve the hemodynamics， adjust the immune responses of the body，and significantly accelerate the recovery of the disease.